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The ADEM trial

ADEM trial results published: Methotrexate disappoints in hand osteoarthritis


Monday 11 November: 11:00–12:30, Hall B1, Georgia World Congress Center, Atlanta, USA

Presenter: Christian Roux, Université Cote d'Azur, Nice, France

In this phase III trial, patients with symptomatic erosive hand osteoarthritis were given once weekly methotrexate 10 mg or placebo for 1 year. The primary endpoint is pain at 3 months, and secondary endpoints include clinical and radiographic features.

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