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Bone diseases

Pathophysiology

26-06-2018 | Osteoporosis | Article

Clinical characteristics and bisphosphonates treatment of rare pregnancy- and lactation-associated osteoporosis

Li L et al. Clin Rheumatol 2018. doi: 10.1007/s10067-018-4185-0

12-04-2018 | Osteoporosis | Article

Testosterone and Male Osteoporosis

Shin DE et al. Clinic Rev Bone Miner Metab 2018; Advance online publication. doi: 10.1007/s12018-018-9245-0

04-04-2018 | Osteoporosis | Review | Article

Understanding osteoporotic pain and its pharmacological treatment

Vellucci R et al. Osteoporos Int 2018; Advance online publication. doi: 10.1007/s00198-018-4476-y

23-02-2018 | Osteoporosis | Review | Article

Good, bad, or ugly: The biological roles of bone marrow fat

Singh L et al. Curr Osteoporos Rep 2018; Advance online publication. doi: 10.1007/s11914-018-0427-y

19-02-2018 | Osteoporosis | Review | Article

Marrow fat: A new target to treat bone diseases?

Lecka-Czernik B et al. Curr Osteoporos Rep 2018; Advance online publication. doi: 10.1007/s11914-018-0426-z

30-01-2018 | Pathophysiology | Review | Article

mTOR signaling in skeletal development and disease

Chen J, Long F. Bone Res 2018; 6: 1. doi: 10.1038/s41413-017-0004-5

15-01-2018 | Osteoporosis | Review | Article

Regulation of bone metabolism by microRNAs

Taipaleenmäki H. Curr Osteoporos Rep 2018; 16: 1. doi: 10.1007/s11914-018-0417-0

19-12-2017 | Rheumatoid arthritis | Review | Article

Joint diseases: From connexins to gap junctions

Donahue HJ, Qu RW, Genetos DC. Nat Rev Rheumatol 2018; 14: 42–51. doi: 10.1038/nrrheum.2017.204

30-03-2017 | Ankylosing spondylitis | Review | Article

The paradox of bone formation and bone loss in ankylosing spondylitis: Evolving new concepts of bone formation and future trends in management

In this article, the authors briefly review the molecular mechanisms that lead to structural damage in ankylosing spondylitis and the impact of treatment with biologics to retard this process.

Magrey MN, Khan MA. Curr Rheumatol Rep 2017;19:17. doi:10.1007/s11926-017-0644-x

17-03-2017 | Osteoporosis | Review | Article

Transient osteoporosis of the hip: Review of the literature

The authors provide an overview of transient osteoporosis of the hip, covering the epidemiology, pathophysiology, etiology, diagnosis, treatment, and potential complications of the condition.1

Asadipooya K, Graves L, Greene LW. Osteoporos Int 2017;28:1805–1816. doi:10.1007/s00198-017-3952-0

07-03-2017 | Osteoporosis | Review | Article

The utility of biomarkers in osteoporosis management

This paper analyzes the most promising new bone marker candidates and reviews the clinical utility of classical and novel markers for the management of postmenopausal osteoporosis.

Garnero P. Mol Diagn Ther 2017. doi:10.1007/s40291-017-0272-1

19-12-2016 | Paget's disease | Review | Article

Clinical and genetic advances in Paget’s disease of bone: A review

Alonso N, Calero-Paniagua I, del Pino-Montes J. Clinic Rev Bone Miner Metab 2017; 15: 37. doi: 10.1007/s12018-016-9226-0

21-09-2016 | Osteoporosis | Book Chapter | Article

Pathogenesis of osteoporosis

The authors provide a concise overview of the pathogenesis of osteoporosis looking at where and how bone resorption occurs and questioning how fragility can be reduced.

Bone Disorders. Springer International Publishing Switzerland, 2017. doi:10.1007/978-3-319-29182-6_18

Authors:
Reiner Bartl, Christoph Bartl

19-08-2016 | Osteoporosis | Book Chapter | Article

Osteoporosis: Pathophysiology and clinical aspects

Mikosch gives a description of the clinical presentation of patients with osteoporosis to show the connection between clinical manifestations and their underlying cellular mechanisms.

Mikosch P. In: Principles of Osteoimmunology. Edited by Pietschmann P. Springer International Publishing Switzerland, 2016. doi:10.1007/978-3-319-34238-2_7

12-07-2016 | Osteoporosis | Book Chapter | Article

Genetics of osteoporosis in older age

In this chapter, the authors review the importance of genetic risk factors for the development of generalized osteoporosis and in relation to fracture rates in the elderly.

Karasik D, Kiel DP. In: Osteoporosis in Older Persons. Edited by Duque G, Kile DP. Springer International Publishing Switzerland, 2016. doi:10.1007/978-3-319-25976-5_8

01-01-2016 | Osteoporosis | Book Chapter | Article

Osteoporosis: Pathophysiology and epidemiology

This chapter explores the epidemiology of osteoporosis and fragility fracture, cell biology and biomechanics, and the latest research on global trends in age- and sex-specific fracture rates.

Moon RJ, Cooper C, Harvey NC. In: The Duration and Safety of Osteoporosis Treatment. Edited by Silverman S, Abrahamsen B. Springer International Publishing Switzerland, 2016. doi:10.1007/978-3-319-23639-1_1

01-01-2016 | Osteoporosis | Book Chapter | Article

Osteoporosis and mechanisms of skeletal aging

This chapter provides an overview of the pathogenesis and evaluation of osteoporosis and fractures in the elderly as well as discussing the molecular and cellular mechanisms relevant to aging.

Glowacki J, Vokes T. In: Advances in Geroscience. Edited by Sierra F, Kohanski R. Springer International Publishing Switzerland, 2016. doi:10.1007/978-3-319-23246-1_10

21-04-2015 | Osteoporosis | Review | Article

A look behind the scenes: the risk and pathogenesis of primary osteoporosis

This review discusses the main heritable and non-heritable factors that contribute to the pathogenesis of primary osteoporosis, focusing on the genetic and epigenetic basis of polygenic osteoporosis.

Nat Rev Rheumatol 2015;11:462–474. doi:10.1038/nrrheum.2015.48

Authors:
Gretl Hendrickx, Eveline Boudin, Wim Van Hul
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