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Connective tissue diseases


09-07-2019 | Systemic lupus erythematosus | Highlight | News

Pregnancy outcomes improving for women with SLE

In the past two decades pregnancy outcomes, including in-hospital maternal mortality, have improved among women with systemic lupus erythematosus, but further improvements are needed to reduce risks further, US research shows.

20-06-2019 | Systemic lupus erythematosus | Highlight | Article

Systemic lupus erythematosus: Novel therapies and targeted treatments

Andrea Fava and George Stojan review new strategies and agents for the treatment of systemic lupus erythematosus that have most recently showed promise in clinical trials.

07-05-2019 | Systemic lupus erythematosus | Podcast | Article

A closer look at the EULAR guidelines for managing lupus

Antonis Fanouriakis, lead author of the updated EULAR guidelines for the management of lupus, talks to medwireNews about what’s new in these guidelines and how they will influence clinical practice.

25-02-2019 | Vaccination | Highlight | News

Immunogenicity of influenza vaccine confirmed in patients with rheumatic disease

Influenza vaccination gives rise to an adequate immune response among patients with rheumatic conditions, researchers report.

29-01-2019 | Lupus nephritis | Editorial | Article

Emerging therapies for lupus nephritis

Lupus nephritis is the most common organ-threatening complication of systemic lupus erythematosus, and current treatment regimens are only partially effective and are potentially toxic. In this editorial, the authors focus on emerging therapeutics to treat this disease.

02-01-2019 | Systemic lupus erythematosus | Highlight | News

Add-on omalizumab shows potential for SLE

Preliminary results from a phase Ib trial suggest that add-on treatment with the anti-IgE antibody omalizumab may be a feasible option for patients with systemic lupus erythematosus.

14-12-2018 | Systemic sclerosis | Case study | Article

A systemic sclerosis patient who has undergone autologous stem cell transplantation

Daniel Furst and Nihal Fathi present a case of a patient with diffuse systemic sclerosis who undergoes autologous hematopoietic stem cell transplantation after failing two other therapies.

24-10-2018 | Pediatric | ACR/ARHP 2018 | Video

Expert highlights: Sangeeta Sule

Editorial board member Sangeeta Sule discusses her highlights from the pediatric rheumatology sessions at the 2018 ACR/ARHP Annual Meeting in Chicago, Illinois, USA (2:14).

24-10-2018 | Systemic lupus erythematosus | ACR/ARHP 2018 | Video

Ustekinumab shows potential for the treatment of SLE

Ronald van Vollenhoven discusses phase II trial results demonstrating that the interkeukin-12/23 inhibitor ustekinumab may be a promising treatment option for systemic lupus erythematosus (5:36).

18-10-2018 | Infection | Editorial | Article

Vaccination in children and adolescents with rheumatic conditions

In this editorial, the authors discuss the risks of live vaccination in children taking antirheumatic medications and how to manage these, as well as how health authorities can address decreasing vaccination coverage of the general public.

16-10-2018 | Pregnancy | Editorial | Article

Planning and managing pregnancy in lupus patients

Megan Clowse discusses the importance of planning pregnancy in patients with lupus to avoid high-risk pregnancy, and outlines strategies to manage active lupus during pregnancy.

31-08-2018 | Immune checkpoint inhibitor-induced rheumatic disease | Review | Article

Rheumatic immune-related adverse events from cancer immunotherapy

Calabrese LH, Calabrese C, Cappelli LC. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0074-9

07-09-2018 | Treatment | Feature | Article

At a glance: Common scores used in rheumatology

A quick-reference guide to the scores that are commonly used in clinical trials and daily rheumatology practice.

03-08-2018 | Sjögren’s syndrome | Highlight | News

Oral microbiome imbalance reported in Sjögren’s syndrome patients

Study results suggest that patients with primary Sjögren’s syndrome, and those with similar symptoms, may experience dysbiosis of the buccal mucosa microbiome.

11-07-2018 | Arthroplasty | Review | Article

Total joint arthroplasty in patients with inflammatory rheumatic diseases

Compagnoni R, Gualtierotti R, Randelli P. Adv Ther 2018. doi: 10.1007/s12325-018-0750-9

11-07-2018 | Pediatric | Review | Article

Pediatric Rheumatology Collaborative Study Group: Over four decades of pivotal clinical drug research in pediatric rheumatology

Brunner HI et al. Pediatr Rheumatol 2018; 16: 45. doi: 10.1186/s12969-018-0261-x

27-06-2018 | Systemic lupus erythematosus | Case report | Article

Acquired angioedema in juvenile systemic lupus erythematosus: Case-based review

Tekin et al. report the case of a previously healthy 16-year-old girl with an acquired angioedema as a rare and initial presentation of systemic lupus erythematosus, and review the related literature.

Tekin ZE, Yener GO, Yüksel S. Rheumatol Int 2018. doi: 10.1007/s00296-018-4088-z

15-06-2018 | Systemic lupus erythematosus | EULAR 2018 | News

Baricitinib shows promise in SLE

The addition of once-daily baricitinib to standard background therapy could improve clinical outcomes in patients with systemic lupus erythematosus, phase II trial findings show.

15-06-2018 | Systemic lupus erythematosus | EULAR 2018 | Video

Expert commentary: Promising results with herpes zoster vaccine in SLE patients

Thomas Dörner comments on study results demonstrating that a live attenuated herpes zoster vaccine is well tolerated and provokes an antibody response in patients with SLE (5:14).

Read the accompanying news story here

12-06-2018 | Physical activity | View from the clinic | Article

Incorporating exercise in the treatment of lupus and other rheumatic diseases: It's time!

In this piece, Sarah Patterson and Patricia Katz discuss the benefits of exercise, and the barriers to increasing physical activity, in patients with systemic lupus erythematosus.

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