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Connective tissue diseases

Systemic lupus erythematosus

Add-on omalizumab shows potential for SLE

Preliminary results from a phase Ib trial suggest that add-on treatment with the anti-IgE antibody omalizumab may be a feasible option for patients with systemic lupus erythematosus.

02-01-2019 | Systemic lupus erythematosus | Highlight | News

Add-on omalizumab shows potential for SLE

Preliminary results from a phase Ib trial suggest that add-on treatment with the anti-IgE antibody omalizumab may be a feasible option for patients with systemic lupus erythematosus.

Source:

Arthritis Rheumatol 2018; doi:10.1002/art.40828

17-12-2018 | Systemic lupus erythematosus | News

Lupus tied to increased cancer risk

Findings from a meta-analysis indicate that systemic lupus erythematosus is associated with an increased risk for 16 types of cancer.

14-12-2018 | Pediatric | Article

Off-label use of tocilizumab to treat non-juvenile idiopathic arthritis in pediatric rheumatic patients: a literature review

Jung JY et al. Pediatr Rheumatol 2018; 16: 79. doi: 10.1186/s12969-018-0296-z

11-12-2018 | Systemic lupus erythematosus | Article

New therapeutic strategies in systemic lupus erythematosus management

Gatto M et al. Nat Rev Rheum 2018. doi: 10.1038/s41584-018-0133-2

Ustekinumab shows potential for the treatment of SLE

Ronald van Vollenhoven discusses phase II trial results demonstrating that the interkeukin-12/23 inhibitor ustekinumab may be a promising treatment option for systemic lupus erythematosus (5:36).

24-10-2018 | Pediatric | ACR/ARHP 2018 | Video

Expert highlights: Sangeeta Sule

Editorial board member Sangeeta Sule discusses her highlights from the pediatric rheumatology sessions at the 2018 ACR/ARHP Annual Meeting in Chicago, Illinois, USA (2:14).

24-10-2018 | Systemic lupus erythematosus | ACR/ARHP 2018 | Video

Ustekinumab shows potential for the treatment of SLE

Ronald van Vollenhoven discusses phase II trial results demonstrating that the interkeukin-12/23 inhibitor ustekinumab may be a promising treatment option for systemic lupus erythematosus (5:36).

Vaccination in children and adolescents with rheumatic conditions

In this editorial, the authors discuss the risks of live vaccination in children taking antirheumatic medications and how to manage these, as well as how health authorities can address decreasing vaccination coverage of the general public.

18-10-2018 | Infection | Editorial | Article

Vaccination in children and adolescents with rheumatic conditions

In this editorial, the authors discuss the risks of live vaccination in children taking antirheumatic medications and how to manage these, as well as how health authorities can address decreasing vaccination coverage of the general public.

Author:
NM Wulffraat, AM de Groot, EES Nieuwenhuis

Planning and managing pregnancy in lupus patients

Megan Clowse discusses the importance of planning pregnancy in patients with lupus to avoid high-risk pregnancy, and outlines strategies to manage active lupus during pregnancy.

16-10-2018 | Pregnancy | Editorial | Article

Planning and managing pregnancy in lupus patients

Megan Clowse discusses the importance of planning pregnancy in patients with lupus to avoid high-risk pregnancy, and outlines strategies to manage active lupus during pregnancy.

Author:
Megan EB Clowse

10-10-2018 | Systemic lupus erythematosus | News

Musculoskeletal inflammation in SLE not reliably identified with existing clinical instruments

Existing classification systems for musculoskeletal symptoms in people with systemic lupus erythematosus fail to identify inflammation in a large proportion of those with synovitis, suggest findings reported in Rheumatology.

Source:

Rheumatology 2018; doi:10.1093/rheumatology/key277

26-09-2018 | Systemic lupus erythematosus | News

Depression linked to increased SLE risk

Women with a history of depression are more than twice as likely as those without depression to develop systemic lupus erythematosus, shows an analysis of data from the Nurses’ Health Study.

Source:

JAMA Psychiatry 2018; doi:10.1001/jamapsychiatry.2018.2462

07-09-2018 | Treatment | Feature | Article

At a glance: Common scores used in rheumatology

A quick-reference guide to the scores that are commonly used in clinical trials and daily rheumatology practice.

23-08-2018 | Systemic lupus erythematosus | News

News in brief

Noninvasive method could detect subclinical cardiac impairment in SLE patients

Cardiac magnetic resonance imaging could be used to identify subclinical cardiac impairment in patients with systemic lupus erythematosus, researchers report.

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