Skip to main content
main-content
Top

27-09-2021 | COVID-19 | News

News in brief

​​​​​​​mRNA COVID-19 vaccines well tolerated in young people with JIA

Author:
Claire Barnard

medwireNews: The Pfizer–BioNTech (BNT162b2) vaccine against SARS-CoV-2 is well tolerated and does not cause disease flares in young people with juvenile idiopathic arthritis (JIA) treated with tumor necrosis factor (TNF) inhibitors, suggest findings from a small study.

Dimitra Dimopoulou and colleagues from the National and Kapodistrian University of Athens in Greece evaluated data from 21 young people aged 16–21 years (median 17 years) with JIA in clinical remission who received both doses of the vaccine in April–May 2021. The majority of participants (74%) experienced local reactions, while less than a fifth (19%) experienced systemic reactions such as headache, fatigue, myalgia, or transient arthralgia.

The researchers say that neither the type of JIA – polyarticular or psoriatic JIA or enthesitis-related arthritis – nor treatment with etanercept versus adalimumab influenced rates of local or systemic reactions. There were no cases of JIA exacerbation based on JADAS-27 scores measured at 1 month prior to vaccination and 1 and 3 months after.

Despite the small patient numbers in the study, “it may be concluded that the vaccine assures an adequate safety and tolerability profile and [does not provoke] disease flare” in adolescents with JIA, write Dimopoulou et al in a letter to Arthritis & Rheumatology.

medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2021 Springer Healthcare Ltd, part of the Springer Nature Group

27 September 2021: The coronavirus pandemic is affecting all healthcare professionals across the globe. Medicine Matters’ focus, in this difficult time, is the dissemination of the latest data to support you in your research and clinical practice, based on the scientific literature. We will update the information we provide on the site, as the data are published. However, please refer to your own professional and governmental guidelines for the latest guidance in your own country.

Arthritis Rheumatol 2021; doi:10.1002/art.41977

COVID-19 vaccination in patients with rheumatic diseases

Get answers to key questions with recommendations from professional organizations

ACR Convergence 2021 highlights

3–9 November: Preview the conference with session recommendations and updates on upcoming coverage.