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05-06-2017 | Image

Figure 3: Patient stratification on the basis of RA-associated bacteria.

(ac) Relative abundance of L. salivarius MLGs in fecal (a), dental (b) and salivary (c) samples from patients with very active (filled circles) and moderately active (open circles) RA (P = 0.017, 0.036 and 0.084, respectively; Wilcoxon rank-sum test). The MLG identification numbers are 2169 (gut), 16600 (dental) and 4643 (salivary) (Supplementary Tables 4, 10 and 11). The disease classification followed EULAR criteria: moderate, 3.2 < DAS28 ≤ 5.1; very active, DAS28 > 5.1 (Supplementary Table 1).