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05-06-2017 | Image

Figure 4: Correlation between gut and oral MLGs.

(a,b) Spearman's correlation between the relative abundances of gut and dental (a) or gut and salivary (b) MLGs (≥100 genes) were calculated for subjects with full sets of fecal, dental and salivary samples (n = 69). Sizes of nodes reflect the number of genes in each MLG. MLGs are colored according to body site and enrichment (yellow, control gut; green, RA gut; blue, control dental; red, RA dental; purple, control saliva; magenta, RA saliva). MLG identification numbers are listed in parentheses if more than one MLG annotated to the same species or unclassified species in a genus (sp.). Blue edges, Spearman's correlation coefficient > 0.4, P < 0.05; red edges, Spearman's correlation coefficient < −0.4, P < 0.05.