14-03-2017 | Gout | Article
Sex differences in gout characteristics: tailoring care for women and men
Journal: BMC Musculoskeletal Disorders
Authors: Leslie R. Harrold, Carol J. Etzel, Allan Gibofsky, Joel M. Kremer, Michael H. Pillinger, Kenneth G. Saag, Naomi Schlesinger, Robert Terkeltaub, Vanessa Cox, Jeffrey D. Greenberg
Publisher: BioMed Central
Abstract
Background
To characterize the differences between women and men with gout.
Methods
We analyzed a US national cohort of gout patients cared for by rheumatologists.
Results
Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).
Conclusions
The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.