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Patients with rheumatic disease often have one or more comorbid conditions. Improving our understanding of these comorbid conditions, particularly shared etiology of these conditions with rheumatic disease, may enhance our understanding of the pathophysiology of rheumatic diseases. Such increased understanding would improve our ability to effectively treat both the rheumatic disease and the comorbid conditions. Increased physician awareness of these frequent comorbid conditions is important to ensure optimal treatment of the patient to improve overall quality of life as well as rheumatic disease-specific outcomes.

This themed collection comprises a selection of recent full-text articles and chapters from the Springer Nature portfolio that discuss this important subject.