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CASE REPORT
Tocilizumab for refractory organising pneumonia associated with Sjögren's disease
  1. Aurelien Justet1,2,
  2. Sebastien Ottaviani3,
  3. Philippe Dieudé3,
  4. Camille Taillé1,2
  1. 1Department of Service de Pneumologie A, Hôpital Bichat-Claude Bernard, Paris, France
  2. 2Université Denis Diderot, Paris 7, Unité INSERM U1152, Paris, France
  3. 3Department of Service de Rhumatologie, Hôpital Bichat Claude Bernard, Paris, France
  1. Correspondence to Dr Aurelien Justet, aurelienjustet{at}yahoo.fr

Summary

Lung involvement in primary Sjögren syndrome occurs in approximately 10–20% of patients. Tocilizumab, an anti-interleukin-6 receptor antibody, has demonstrated efficacy and safety in small series of systemic sclerosis, and systemic lupus erythematosus, but its effect on interstitial lung manifestations of connective tissue diseases is not well known. We report the use of tocilizumab in a refractory organising pneumonia associated with Sjögren's disease. Our observation suggests that tocilizumab could be an alternative therapeutic in refractory organising pneumonia.

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