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Pediatric rheumatology

Pathophysiology

03-08-2018 | Pathophysiology | Review | Article

S100 proteins in rheumatic diseases

Austermann J, Spiekermann C, Roth J. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0058-9

08-06-2018 | Pain | Review | Article

Cannabinoids for the treatment of rheumatic diseases: Where do we stand?

Katz-Talmor D et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0025-5

16-05-2018 | Juvenile idiopathic arthritis | Review | Article

Vitamin D and juvenile idiopathic arthritis

In this review, Finch et al summarize and evaluate the current literature relating to vitamin D and juvenile idiopathic arthritis.

Finch SL, Rosenberg AM, Vatanparast H. Pediatr Rheumatol 2018; 16: 34. doi: 10.1186/s12969-018-0250-0

Vitamin D and juvenile idiopathic arthritis

In this review, Finch et al summarize and evaluate the current literature relating to vitamin D and juvenile idiopathic arthritis [read more].
Finch SL, Rosenberg AM, Vatanparast H. Pediatr Rheumatol 2018; 16: 34. doi: 10.1186/s12969-018-0250-0

08-05-2018 | Kawasaki disease | Review | Article

Circulating adipokines are associated with Kawasaki disease

Zhang X et al. Pediatr Rheumatol 2018; 16: 33. doi: 10.1186/s12969-018-0243-z

21-03-2018 | Pathogenesis | Review | Article

Type I interferon in rheumatic diseases

Wampler TL, Niewold TB. Nat Rev Rheumatol 2018; 14: 214–228. doi: 10.1038/nrrheum.2018.31

09-02-2018 | Kawasaki disease | Article

The association between oxidative stress and endothelial dysfunction in early childhood patients with Kawasaki disease

Ishikawa T, Seki K. BMC Cardiovasc Disord 2018; 18: 30. doi: 10.1186/s12872-018-0765-9

08-02-2018 | Juvenile idiopathic arthritis | Review | Article

Treat to target in juvenile idiopathic arthritis: Challenges and opportunities

Smitherman EA, Consolaro A, Morgan EM. Curr Treat Options in Rheum 2018; 4: 29–43. doi: 10.1007/s40674-018-0090-6

08-02-2018 | Juvenile idiopathic arthritis | Article

Association of interferon regulatory factor 5 (IRF5) gene polymorphisms with juvenile idiopathic arthritis

Esmaeili Reykande S et al. iClin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4010-9

24-01-2018 | Pathogenesis | Review | Article

Moving towards a molecular taxonomy of autoimmune rheumatic diseases

Barturen G et al. Nat Rev Rheumatol 2018; 14: 75–93. doi: 10.1038/nrrheum.2017.220

07-08-2017 | Vasculitis | Review | Article

Vasculitis update: Pathogenesis and biomarkers

Brogan & Eleftheriou summarize recent advances in the understanding of the pathophysiology of primary systemic vasculitides and the potential role of novel biomarkers discovered in that context. 

Brogan P, Eleftheriou D. Pediatr Nephrol 2017. doi:10.1007/s00467-017-3597-4

09-05-2017 | Juvenile idiopathic arthritis | Article

Lectin pathway factors in patients suffering from juvenile idiopathic arthritis

The findings of this study suggest a possible role for the lectin pathway in the pathogenesis of juvenile idiopathic arthritis, perhaps secondary to a role in host defense.

Immunol Cell Biol 2017;95:666-675. doi:10.1038/icb.2017.31

24-11-2016 | Juvenile idiopathic arthritis | Article

Juvenile arthritis caused by a novel FAMIN (LACC1) mutation in two children with systemic and extended oligoarticular course

A case report reviewing two siblings with severe familial forms of juvenile idiopathic arthritis (JIA) and the causal role of mutations in FAMIN for this and other form of JIA.

Kallinich T et al. Pediatr Rheumatol 2016;14:63. doi:10.1186/s12969-016-0124-2

20-09-2016 | Juvenile idiopathic arthritis | Review | Article

The human microbiome and juvenile idiopathic arthritis

An expert review of the involvement of the microbiome in juvenile idiopathic arthritis (JIA) pathogenesis and how it may influence the development of autoimmunity in JIA.

Verwoerd A et al. Pediatr Rheumatol 2016;14:55. doi:10.1186/s12969-016-0114-4

22-07-2016 | Juvenile idiopathic arthritis | Review | Article

Gut microbiota-host interactions and juvenile idiopathic arthritis

Arvonen et al. discuss the mechanisms by which the the microbiota may influence the risk of juvenile idiopathic arthritis and other systemic inflammatory conditions in children.

Arvonen M et al. Pediatr Rheumatol 2016;14:44. doi:10.1186/s12969-016-0104-6

07-07-2016 | Juvenile idiopathic arthritis | Article

Whole blood expression profiling from the TREAT trial: insights for the pathogenesis of polyarticular juvenile idiopathic arthritis

In this study, whole blood expression profiling distinguishes children with polyarticular juvenile idiopathic arthritis from healthy controls and identifies pathways of biologic relevance.

Jiang K et al. Arthritis Res Ther 2016;18:157. doi:10.1186/s13075-016-1059-1

02-07-2016 | Juvenile idiopathic arthritis | Review | Article

Network analysis and juvenile idiopathic arthritis (JIA): a new horizon for the understanding of disease pathogenesis and therapeutic target identification

This review highlights findings in systems biology related to juvenile idiopathic arthritis (JIA) in an attempt to assist in the understanding of JIA pathogenesis and therapeutic target identification.

Donn R et al. Pediatr Rheumatol 2016;14:40. doi:10.1186/s12969-016-0078-4

16-01-2016 | Myositis | Review | Article

The immune response and the pathogenesis of idiopathic inflammatory myositis: A critical review

Ceribelli A et al. Clinic Rev Allerg Immunol 2017; 52: 58–70. doi: 10.1007/s12016-016-8527-x

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