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Rheumatoid arthritis

Clinical trials

20-10-2018 | Rheumatoid arthritis | Article

On-drug and drug-free remission by baseline symptom duration: Abatacept with methotrexate in patients with early rheumatoid arthritis

Bykerk VP et al. Rheumatol Int 2018; 38: 2225–2231. doi: 10.1007/s00296-018-4173-3

17-08-2018 | Rheumatoid arthritis | Article

Modified- versus immediate-release tofacitinib in Japanese rheumatoid arthritis patients: A randomized, phase III, non-inferiority study

Tanaka Y et al. Rheumatology (Oxford) 2018: key250. doi: 10.1093/rheumatology/key250

Clinical, ultrasound, and predictability outcomes following certolizumab pegol treatment (with methotrexate) in patients with moderate-to-severe rheumatoid arthritis: 52-week results from the CZP-SPEED study

The aim of this trial was to assess the impact of certolizumab pegol treatment on clinical, patient-reported, and musculoskeletal ultrasound outcomes in Italian patients with rheumatoid arthritis [read more].
Sarzi-Puttini P et al. Adv Ther 2018. doi: 10.1007/s12325-018-0751-8

Similar pharmacokinetics of the adalimumab (Humira®) biosimilar BI 695501 whether administered via subcutaneous autoinjector or prefilled syringe (VOLTAIRE®-AI and VOLTAIRE®-TAI): Phase 1, randomized, open-label, parallel-group trials

The authors present two phase 1 studies comparing the pharmacokinetics, safety, and immunogenicity of adalimumab biosimilar BI 695501 delivered via autoinjector versus prefilled syringe [read more].
Ramael S et al. Rheumatol Ther 2018. doi: 10.1007/s40744-018-0119-1

29-06-2018 | Adalimumab biosimilar | Article

Similar pharmacokinetics of the adalimumab (Humira®) biosimilar BI 695501 whether administered via subcutaneous autoinjector or prefilled syringe (VOLTAIRE®-AI and VOLTAIRE®-TAI): Phase 1, randomized, open-label, parallel-group trials

The authors present two phase 1 studies comparing the pharmacokinetics, safety, and immunogenicity of adalimumab biosimilar BI 695501 delivered via autoinjector versus prefilled syringe.

Ramael S et al. Rheumatol Ther 2018. doi: 10.1007/s40744-018-0119-1

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