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04-10-2016 | Systemic lupus erythematosus | Book Chapter | Article

4. Systemic Lupus Erythematosus: Clinical Aspects

Authors: Savino Sciascia, Maria Josè Cuadrado

Publisher: Springer International Publishing

Abstract

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that results from a combination of genetic, environmental, and hormonal factors. The disease is characterized by a heterogeneous clinical presentation, a different course in different individuals, and a variability in the disease progression/fluctuations within the same patient. The clinical picture of SLE is extremely variable and may be related to disease activity, organ damage, drug toxicity, and quality of life.

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