04-10-2016 | Systemic lupus erythematosus | Book Chapter | Article
4. Systemic Lupus Erythematosus: Clinical Aspects
Authors: Savino Sciascia, Maria Josè Cuadrado
Publisher: Springer International Publishing
Abstract
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that results from a combination of genetic, environmental, and hormonal factors. The disease is characterized by a heterogeneous clinical presentation, a different course in different individuals, and a variability in the disease progression/fluctuations within the same patient. The clinical picture of SLE is extremely variable and may be related to disease activity, organ damage, drug toxicity, and quality of life.