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Tejpal Gill

Tejpal Gill is a Research Assistant Professor at the Division of Arthritis and Rheumatic Diseases at Oregon Health & Science University, USA.

Dr Gill’s research is focused on determining the host–microbe interactions in HLA-B27-associated spondyloarthropathies. Previously, at the National Institutes of Health, she demonstrated that HLA-B27, a major genetic risk factor for spondyloarthritis (SpA), causes background-dependent gut microbial dysbiosis in an experimental model of SpA. This study emphasized the importance of evaluating microbial communities and their functions, and suggested an ecological model of microbial dysbiosis.

Dr Gill’s broader interests include identification of microbial metabolites with a potential to ameliorate or alleviate SpA and associated gut inflammation. She is particularly interested in teasing out the role of host genetics in addition to HLA-B27 on the development of SpA. With the hypothesis tested in an animal model, her future goals involve patient-oriented clinical research studying the relationship between gut microbes and host immune dysregulation in SpA.

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Microbiome

07-02-2020 | Spondyloarthropathies | Editorial | Article

The microbiome in spondyloarthritis and its relationship with the IL-23/IL-17 axis

Tejpal Gill discusses the relationship between the microbiome and the IL-23/IL-17 axis in spondyloarthritis.