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24 search results for:

Alendronate 

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  1. 11-01-2022 | Osteoporosis | News | Article

    Hip fracture risk higher during risedronate versus alendronate drug holiday

    The risk for hip fracture is higher during a treatment break from risedronate than it is during a break from alendronate, study findings indicate.

  2. 25-04-2019 | Osteoporosis | News | Article

    No difference in fracture risk with denosumab vs alendronate

    Patients initiating denosumab have a similar 3-year fracture risk to those initiating alendronate, regardless of sex, age, or fracture history, show results of a large study among Danish patients in routine clinical practice.

  3. 18-06-2018 | Osteoporosis | Article

    Early use of alendronate as a protective factor against the development of glucocorticoid-induced bone loss in childhood-onset rheumatic diseases: A cross-sectional study

    Inoue, Y et al. Pediatr Rheumatol 2018; 16: 36. doi: 10.1186/s12969-018-0258-5

  4. 18-02-2019 | Osteoporosis | Editorial | Article

    Osteoporosis therapy: Drug holiday or not?

    Extension trials of oral alendronate [8] and intravenous zoledronate [9,10] have shown that a plateau phase in the bone mineral density (BMD) response is established at about 5 years of treatment, with little or no increase in BMD thereafter.

  5. 24-06-2020 | Osteoporosis | News | Article

    ​​​​​​​Cardiovascular safety of romosozumab warrants ‘rigorous assessment’

    Analysis of 25 events from 4298 people indicated that treatment with romosozumab at a dose of 210 mg once monthly was associated with a significant threefold increased risk for cardiac ischemic events relative to alendronate or placebo treatment (odds ratio [OR]=2.98).

  6. 24-04-2019 | Osteoporosis | News | Article

    Long-term drug treatment may reduce fracture risk in women with osteoporosis

    “In women with osteoporosis, indications for long-term raloxifene therapy may be limited because it reduced only vertebral fractures, whereas both long-term use of zoledronic acid and that of alendronate also reduced nonvertebral fractures,” write Fink and team.

  7. 11-04-2019 | Osteoporosis | News | Article
    approvalsWatch

    FDA approves romosozumab for fracture prevention in osteoporosis

    The other trial demonstrated a significantly lower risk with romosozumab versus alendronate, but at the cost of an elevated risk for heart attack, stroke, and cardiovascular death.

  8. 24-04-2019 | Osteoporosis | Highlight | Teaser
    medwireNews top story

    Long-term drug treatment may reduce fracture risk in women with osteoporosis

    Findings from a systematic review suggest that long-term drug treatment is associated with a reduction in fracture risk among women with osteoporosis, with different agents having varying long-term safety profiles.

  9. 31-05-2018 | Osteoporosis | View from the clinic | Article

    Managing osteoporosis in pediatric patients

    Physical therapy and 6 months of treatment with alendronate have helped, and 2 years on she remains pain free.

  10. 06-02-2018 | Osteoporosis | Review | Article

    Efficacy of anti-osteoporotic medications in patients with type 1 and 2 diabetes mellitus: A systematic review

    Anagnostis P et al. Endocrine 2018; Advance online publication. doi: 10.1007/s12020-018-1548-x

  11. 12-10-2017 | Osteoporosis | News | Article

    Romosozumab shows promise for fracture prevention in women with osteoporosis

    Results of the phase III ARCH trial suggest that women with osteoporosis who are treated with romosozumab are less likely to experience fractures, but may have an increased risk for cardiovascular events, compared with those given alendronate.

  12. 04-06-2018 | Osteoporosis | Review | Article

    Review of the guideline of the American College of Physicians on the treatment of osteoporosis

    Kanis, JA et al. Osteoporos Int 2018. doi: 10.1007/s00198-018-4504-y

  13. 17-05-2018 | Osteoporosis | Article

    Anti-osteoporosis drug use: Too little, too much, or just right? The HUNT study, Norway

    Hoff M et al. Osteoporos Int 2018. doi: 10.1007/s00198-018-4560-3

  14. 02-05-2018 | Osteoporosis | Review | Article

    Novel imaging modalities in osteoporosis diagnosis and risk stratification

    Haque S et al. Curr Treat Options in Rheum 2018; Advance online publication. doi: 10.1007/s40674-018-0099-x

  15. 06-11-2017 | Osteoporosis | News | Article

    Bisphosphonate ‘drug holidays’ linked to increased hip fracture risk

    Participants were aged a mean of 78.5 years, and the majority were treated with alendronate, with almost three quarters (71.7%) of women having used alendronate at any time, and just over half (52.0%) given the drug exclusively.

  16. 19-04-2017 | Osteoporosis | Review | Article

    UK clinical guideline for the prevention and treatment of osteoporosis

    This guideline, accredited by the National Institute of Health and Care Excellence, provides an overview of the assessment and management of osteoporosis for all healthcare professionals who are involved in its management. Compston J, Cooper A, Cooper C et al. Arch Osteoporos 2017;12:43. doi:10.1007/s11657-017-0324-5

  17. 26-02-2017 | Osteoporosis | Book Chapter | Article

    New target sites for treatment of osteoporosis

    This chapter summarizes recent updates in the development of anti-osteoporotic agents, focusing on approaches based on the application of inorganic polymers and combination therapy. Müller WEG, Schröder HC, Wang X. In: Blue Biotechnology . Edited by Müller WEG, Schröder HC, Wang X. Springer International Publishing AG, 2017. doi:10.1007/978-3-319-51284-6_6

  18. 12-07-2016 | Osteoporosis | Book Chapter | Article

    Medical treatment of age related osteoporosis

    An expert summary of available therapies and those on the horizon for patients with osteoporosis including vitamin D, bisphosphonates, selective estrogen receptor modulators, denosumab, and teriparatide. Wong EK-C, Kim LH-Y, Papaioannou A. In: Osteoporosis in Older Persons . Edited by Duque G, Kile DP. Springer International Publishing Switzerland, 2016. doi:10.1007/978-3-319-25976-5_12

  19. 28-04-2016 | Osteoporosis | Review | Article

    The management of osteoporosis in children

    An expert review of the manifestations of osteoporosis in childhood, recommendations for monitoring and prevention, and suggestions for when a child should be considered a candidate for therapy. Ward LM, Konji VN, & Ma J. Osteoporos Int 2016;27:2147–2179. doi:10.1007/s00198-016-3515-9

  20. 18-01-2016 | Osteoporosis | Article

    Efficacy of osteoporosis pharmacotherapies in preventing fracture among oral glucocorticoid users: a network meta-analysis

    The authors assessed the efficacy of approved osteoporosis pharmacotherapies in preventing fracture and determined that teriparatide, risedronate, and etidronate led to a decreased vertebral fracture risk. Amiche MA et al. Osteoporos Int 2016;27:1989–1998. doi:10.1007/s00198-015-3476-4

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