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13 search results for:

Benzbromarone 

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  1. 05-06-2021 | EULAR 2021 | Conference coverage | Article
    News in brief 

    CV risk similar for gout treatments allopurinol and benzbromarone

    Allopurinol and benzbromarone have comparable cardiovascular risk profiles in patients with gout, suggests research presented in a poster at the EULAR 2021 Virtual Congress.

  2. 22-05-2018 | Gout | Article

    Decreased incidence of diabetes in patients with gout using benzbromarone

    Niu SW et al. Rheumatology (Oxford) 2018. doi: 10.1093/rheumatology/key138

  3. 21-10-2019 | Gout | News | Article

    Achieving target sUA levels ‘should be a principal goal’ in hyperuricemic patients with gout

    All participants achieved remission of gout flares during the study period, most commonly after treatment with allopurinol (62.2%), followed by benzbromarone (17.9%).

  4. 21-06-2018 | Gout | Review | Article

    Predicting response or non-response to urate-lowering therapy in patients with gout

    The authors review the extent of treatment success or failure with the xanthine oxidoreductase inhibitors allopurinol and febuxostat and indicate how the dosage of urate-lowering therapy may be modified to increase the response in the majority of patients with gout. Graham GG et al. Curr Rheumatol Rep 2018; 20: 47. doi: 10.1007/s11926-018-0760-2

  5. 21-06-2018 | Gout | Highlight | Teaser
    Journal article

    Predicting response or non-response to urate-lowering therapy in patients with gout

    The authors review the extent of treatment success or failure with the xanthine oxidoreductase inhibitors allopurinol and febuxostat and indicate how the dosage of urate-lowering therapy may be modified to increase the response in the majority of patients with gout [ read more ]. Graham GG et al. Curr Rheumatol Rep 2018; 20: 47. doi: 10.1007/s11926-018-0760-2

  6. 01-06-2018 | Gout | Article

    Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricemia: A phase 2a, open-label study

    Shiramoto M et al. Rheumatology (Oxford) 2018: key100. doi: 10.1093/rheumatology/key100

  7. 21-02-2018 | Gout | Editorial | Article

    Gout therapies and cardiovascular risk

    Benzbromarone or pegloticase are alternatives, but are not available in many countries.

  8. 13-02-2018 | Gout | Review | Article

    Managing gout in the patient with renal impairment

    Pascual E, Sivera F, Andrés M. Drugs Aging 2018; Advance online publication. doi: 10.1007/s40266-018-0517-7

  9. 30-10-2017 | Gout | Editorial | Article

    Evolution or revolution in urate-lowering therapies for gout?

    ., Development of new urate-lowering medications Historically, drug development failures in other indications have been the most common source of urate-lowering medications in the 20 th century: allopurinol was a failed anti-mitotic; benzbromarone a failed antihypertensive; and sulfinpyrazone a failed nonsteroidal anti-inflammatory drugs.

  10. 31-08-2017 | Gout | News | Article

    Lifestyle modification might improve ULT response in gout patients

    Most participants (83.8%) were male, and the majority of patients were prescribed allopurinol (71.7%), with the remainder taking febuxostat, probenecid, or benzbromarone.

  11. 08-09-2016 | Gout | Article

    Comparative efficacy and safety of urate-lowering therapy for the treatment of hyperuricemia: a systematic review and network meta-analysis

    Benzbromarone was introduced as a uricosuric drug in the 1970s.

  12. 30-05-2014 | Gout | Book Chapter | Article

    Physiopathology of gout

    The most effective uricosuric drug tested in clinical practice is benzbromarone, a drug that exerts intense inhibition of URAT1 activity, although is not widely available for clinical use [6].

  13. 26-09-2014 | Gout | Article

    Urate-lowering therapy: current options and future prospects for elderly patients with gout

    This paper discusses the use of urate-lowering therapies in elderly patients, with a focus on the available therapeutic options and their risks and benefits in this patient population, as well as a mention of pipeline therapeutics. Stamp LK, Chapman PT.  Drugs Aging . 2014;31:777–786. doi: 10.1007/s40266-014-0214-0.

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