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Biologics 

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  1. 05-08-2022 | Biologics | News | Article

    Support for long-term use of biologics in people with HIV

    Taken together, these findings suggest that biologics “provide a means for achieving symptomatic remission without major adverse opportunistic infections or any detrimental effects on CD4 counts or viral load,” write the authors in RMD Open .

  2. 02-02-2022 | Ankylosing spondylitis | Adis Journal Club | Article
    Advances in Therapy

    Disease Activity-Guided Stepwise Tapering but Not Discontinuation of Biologics Is a Feasible Therapeutic Strategy for Patients with Ankylosing Spondylitis: Real-World Evidence

    Our work conducted real-world retrospective studies about tumor necrosis factor inhibitor (TNFi) treatment and found that spontaneous dose reduction of biologics after the symptom relief was a common phenomenon in patients with AS in China.

  3. 04-10-2021 | Psoriatic arthritis | News | Article

    Functional outomes favored by patients with PsA when choosing biologics

    Half of the participants were receiving a biologic at the time of the experiment, while 53.3% had prior experience with biologics (more than one biologic in 31.3% of patients).

  4. 04-07-2021 | Adis Journal Club | Article
    Rheumatology and Therapy

    Features and Outcomes of Microcrystalline Arthritis Treated by Biologics: A Retrospective Study

  5. 06-07-2021 | Psoriatic arthritis | News | Article

    Biologics may reduce PsA risk in patients with psoriasis

    The annual incidence rate for PsA was 1.20 cases per 100 patients for those taking biologics versus 2.17 cases per 100 patients for those given phototherapy.

  6. 18-06-2021 | Adis Journal Club | Article
    The Patient - Patient-Centered Outcomes Research

    Towards Personalising the Use of Biologics in Rheumatoid Arthritis: A Discrete Choice Experiment

    Objective This study quantified preferences for an algorithm-guided approach to prescribing biologics (termed ‘biologic calculator’).

  7. 07-06-2021 | EULAR 2021 | Conference coverage | Article

    Real-world studies point to similar effectiveness of JAK inhibitors and biologics

    Findings from two real-world studies presented at the EULAR 2021 Virtual Congress suggest that JAK inhibitors and biologics are similarly effective for the treatment of inflammatory arthritis.

  8. 04-06-2021 | EULAR 2021 | Conference coverage | Article

    Race, ethnicity may influence response to non-TNF inhibitor biologics in RA patients

    Findings from a large real-world rheumatoid arthritis study suggest that non-tumor necrosis factor inhibitor biologics are associated with lower disease activity than TNF inhibitors among Black and Asian patients, as well as those with non-Hispanic ethnicity.

  9. 29-04-2021 | BSR 2021 | Conference coverage | Article
    News in brief

    ​​​​​​​COVID-19 outcomes described in children with rheumatic diseases taking biologics

    BSR 2021: A Russian study has evaluated COVID-19 outcomes in children with rheumatic diseases taking biologics.

  10. 16-04-2021 | Rheumatoid arthritis | News | Article

    Real-world data reinforce benefit of optimizing methotrexate before starting biologics

    Cécile Gaujoux-Viala (CHU de Nîmes, France) and colleagues warn that due to fewer patients starting biologics than optimizing methotrexate treatment, “[t]he two most common therapeutic strategies should be compared with caution.”

  11. 28-01-2021 | COVID-19 | News | Article

    COVID-19 risk not increased in rheumatic disease patients taking biologics, JAK inhibitors

    In patients with chronic inflammatory arthritis, biologics and JAK inhibitors are associated with a reduced risk for confirmed or highly suspected COVID-19, but glucocorticoids are associated with an increased risk, according to a survey of patients in Northern Italy.

  12. 11-11-2020 | ACR 2020 | Conference coverage | Article

    ‘The Great Debate’: JAK inhibitors vs biologics following methotrexate failure in RA

    “The Great Debate” of the ACR Convergence 2020 virtual meeting addressed the question of whether JAK inhibitors should be given before biologics following an inadequate response to methotrexate in patients with rheumatoid arthritis.

  13. 12-11-2020 | Rheumatoid arthritis | Highlight | Teaser
    ACR Convergence 2020 news

    ‘The Great Debate’: JAK inhibitors vs biologics following methotrexate failure in RA

    “The Great Debate” of the ACR Convergence 2020 virtual meeting addressed the question of whether JAK inhibitors should be given before biologics following an inadequate response to methotrexate in patients with rheumatoid arthritis.

  14. 08-07-2020 | Rheumatoid arthritis | News | Article

    ‘Minor differences’ between biologics for the treatment of RA

    A systematic review and network meta-analysis finds few significant differences in the benefits and harms associated with different biologics when given in combination with methotrexate for the treatment of rheumatoid arthritis.

  15. 08-07-2020 | Rheumatoid arthritis | Highlight | Teaser
    medwireNews top story

    ‘Minor differences’ between biologics for the treatment of RA

    A systematic review and network meta-analysis finds few significant differences in the benefits and harms associated with different biologics when given in combination with methotrexate for the treatment of rheumatoid arthritis.

  16. 27-07-2020 | Rheumatoid arthritis | News | Article

    Similar RA outcomes with TNF inhibitors vs other biologics, JAK inhibitors

    medwireNews : Findings from two real-world studies suggest that rheumatoid arthritis patients treated with TNF inhibitors experience similar clinical outcomes and rates of discontinuation to those given other biologics or JAK inhibitors.

  17. 13-11-2019 | Rheumatoid arthritis | ACR/ARP 2019 | Article

    Methotrexate plus glucocorticoids compare favorably with biologics in early RA

    Study findings pitting methotrexate plus glucocorticoid treatment against methotrexate plus one of three biologics in early rheumatoid arthritis provide support for the active conventional treatment.

  18. 12-11-2019 | Rheumatoid arthritis | ACR/ARP 2019 | Article
    News in brief

    Comparable effectiveness of biologics regardless of age at RA onset

    Rheumatoid arthritis patients gain similar benefits from biologic treatment irrespective of whether they develop the disease before or after the age of 60 years, study findings suggest.

  19. 31-03-2020 | Rheumatoid arthritis | News | Article

    Support for combining non-methotrexate csDMARDs with biologics in RA patients

    Non-methotrexate conventional synthetic csDMARDs may be “efficient alternatives” to methotrexate for using in combination with biologics for the treatment of rheumatoid arthritis, researchers report.

  20. 25-02-2020 | Psoriatic arthritis | News | Article

    Network meta-analysis highlights ‘generally few’ differences among biologics in PsA

    In the safety analysis, none of the biologics were associated with a significantly higher or lower risk for experiencing a treatment-emergent adverse event (TEAE) relative to placebo or any of the other biologics.

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