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21 search results for:

Celecoxib 

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  1. 26-06-2020 | Osteoarthritis | News | Article

    Noninferiority of diacerein to celecoxib demonstrated for knee OA pain

    Diacerein has comparable efficacy to celecoxib for pain reduction in patients with moderate-to-severe symptomatic knee osteoarthritis and is well tolerated, suggest study findings reported in Rheumatology.

  2. 05-06-2017 | Osteoarthritis | News | Article

    Chondroitin sulfate as good as celecoxib for knee OA

    Results of a randomized trial suggest that pharmaceutical-grade chondroitin sulfate is as effective as the non-steroidal anti-inflammatory drug celecoxib for reducing pain and improving function among patients with symptomatic knee osteoarthritis.

  3. 19-04-2017 | NSAIDs | News | Article

    Celecoxib linked to reduced GI bleeding risk in patients with arthritis, cardiothrombotic disease

    Results of the CONCERN trial suggest that celecoxib is associated with a lower risk for recurrent upper gastrointestinal bleeding than naproxen among patients with arthritis and cardiothrombotic diseases treated concomitantly with aspirin and non-steroidal anti-inflammatory drugs.

  4. 18-09-2018 | Osteoarthritis | Review | Article

    Fixed-dose combination amlodipine/celecoxib (Consensi) for hypertension and osteoarthritis

    Smith SM, Cooper-DeHoff RM.  Am J Med  2018. doi: 10.1016/j.amjmed.2018.08.027

  5. 11-02-2021 | Osteoarthritis | News | Article

    Long-term data confirm risk to joints with tanezumab

    For the current safety study, patients with WOMAC Pain and Physical Function scores of 5 or more, a fair, poor, or very poor patient’s global assessment of OA (PGA‐OA), a history of inadequate pain relief with standard analgesics, and no history of other bone or joint conditions were randomly assigned to receive subcutaneous tanezumab 2.5 mg (n=1002) or 5.0 mg (n=998) every 8 weeks or to twice‐daily oral naproxen, celecoxib, or diclofenac (n=996), each for 56 weeks followed by a 24-week post‐treatment follow‐up period.

  6. 11-10-2019 | Axial spondyloarthritis | Editorial | Article

    Do current therapies slow radiographic progression in axial spondyloarthritis/ ankylosing spondylitis?

    Wanders et al reported a significant decrease in progression when continuously using NSAIDS (principally celecoxib) compared with intermittent dosages.

  7. 08-08-2019 | Osteoarthritis | News | Article

    NSAIDs contribute ‘substantially’ to increased CVD risk in osteoarthritis

    In a subgroup analysis by NSAID type, the team estimated that around 29% of the OA-associated CVD risk was mediated by conventional NSAIDs including diclofenac, ibuprofen, and naproxen, while 21% was accounted for by selective COX-2 inhibitors including celecoxib, lumiracoxib, rofecoxib, and valdecoxib.

  8. 12-03-2019 | Osteoarthritis | News | Article

    Tramadol linked to increased mortality risk in osteoarthritis patients

    Mortality rates were 23.5 versus 13.8 per 1000 person–years for tramadol versus naproxen, 36.2 versus 19.2 per 1000 person–years for tramadol versus diclofenac, 31.2 versus 18.4 per 1000 person–years for tramadol versus celecoxib, and 25.7 versus 12.8 per 1000 person–years for tramadol versus etoricoxib.

  9. 05-04-2019 | Osteoarthritis | News | Article

    Beneficial effects of NSAIDs peak early in knee osteoarthritis

    When NSAIDs were separated by class, traditional NSAIDs “performed consistently better” than celecoxib and intermediate cyclooxygenase inhibitors in terms of pain, and “outperformed” the other classes in functional improvement, say the researchers.

  10. 21-12-2018 | Osteoarthritis | News | Article

    Long-term impact unclear for knee OA medications

    Glucosamine sulfate remained significantly associated with improvements in pain when data were analyzed on a normalized 1–100 scale and when studies at high risk of bias were excluded from the analysis, but celecoxib did not.

  11. 08-06-2018 | Osteoarthritis | Article

    Disease-modifying effects of COX-2 selective inhibitors and non-selective NSAIDs in osteoarthritis: A systematic review

    Nakata K et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.05.021

  12. 20-04-2018 | Rheumatoid arthritis | Article

    The potential benefits of aspirin for primary cardiovascular prevention in rheumatoid arthritis: A secondary analysis of the PRECISION Trial

    Solomon DH et al. Rheumatology (Oxford)  2018; Advacne online publication. doi: 10.1093/rheumatology/key105

  13. 02-01-2019 | Osteoarthritis | Highlight | Teaser
    medwireNews top story

    Long-term impact unclear for knee OA medications

    Findings from a systematic review and network meta-analysis published in JAMA indicate that it is not clear whether pharmacologic treatments offer long-term benefits for patients with knee osteoarthritis.

  14. 30-08-2017 | Osteoarthritis | News | Article

    Ibuprofen associated with elevated blood pressure in patients with arthritis

    Patients with osteoarthritis or rheumatoid arthritis who take ibuprofen are more likely to experience an increase in systolic blood pressure than those taking celecoxib, results of the PRECISION-ABPM study suggest.

  15. 09-05-2018 | Vasculitis | Case report | Article

    The first case of bacillus Calmette-Guérin-induced small-vessel central nervous system vasculitis

    His only medications were verapamil SR 120 mg daily, celecoxib 200 mg twice daily as needed, and pantoprazole 40 mg daily.

  16. 08-06-2017 | NSAIDs | Editorial | Article

    Cardiovascular risk of non-steroidal anti-inflammatory drugs

    Editorial Board member Oliver FitzGerald reviews the cardiovascular risk of non-steroidal anti-inflammatory drugs such as celecoxib, naproxen, and ibuprofen in light of results from the PRECISION study.

  17. 24-05-2018 | Rheumatoid arthritis | Article

    2017 recommendations of the Brazilian Society of Rheumatology for the pharmacological treatment of rheumatoid arthritis

    Mota LMH et al. Adv Rheumatol 2018; 58: 2. doi: 10.1186/s42358-018-0005-0

  18. 30-04-2018 | Osteoarthritis | Article

    Effects of glucosamine in patients with osteoarthritis of the knee: A systematic review and meta-analysis

    Ogata T et al. Clin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4106-2

  19. 18-08-2015 | Comorbidities | Article

    Cardiovascular comorbidity in rheumatic diseases

    A systematic review and meta-analysis, 151 published in 2015, also identified cardiovascular risk in patients with IJDs, which was largely associated with the use of rofecoxib, and not with NSAIDs or celecoxib.

  20. 11-07-2018 | Pediatric | Review | Article

    Pediatric Rheumatology Collaborative Study Group: Over four decades of pivotal clinical drug research in pediatric rheumatology

    Brunner HI et al. Pediatr Rheumatol 2018; 16: 45. doi: 10.1186/s12969-018-0261-x

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