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Cyclosporine 

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  1. 24-03-2022 | Kawasaki disease | News | Article

    Network meta-analysis rates treatments for Kawasaki disease

    The network meta-analysis (NMA) also revealed that “high-dose IVIG with pulse steroid therapy or cyclosporine therapy might have an additional effect on improving the decline in fever and lowering the incidence of [coronary artery lesions],” report Ping-Tao Tseng (Prospect Clinic for Otorhinolaryngology and Neurology, Kaohsiung, Taiwan) and co-authors in eBioMedicine .

  2. 20-12-2021 | Psoriatic arthritis | News | Article
    approvalsWatch

    FDA approves upadacitinib for selected psoriatic arthritis patients

    Upadacitinib is approved at a dose of 15 mg/day for the treatment of PsA, and is not recommended for use in combination with other JAK inhibitors, biologic DMARDs, or potent immunosuppressants such as azathioprine or cyclosporine.

  3. 10-07-2021 | Adis Journal Club | Article
    Pediatric Drugs

    An Update on the Management of Childhood-Onset Systemic Lupus Erythematosus

    Calcineurin inhibitors (cyclosporine, tacrolimus, voclosporin) appear to be a good option for cSLE patients with lupus nephritis.

  4. 14-10-2020 | Psoriatic arthritis | News | Article

    Latent tuberculosis infection rare among secukinumab users

    The researchers explain that methotrexate, cyclosporine, and tumor necrosis factor inhibitors have been associated with an increased risk for TB and LTBI reactivation.

  5. 15-01-2020 | Myositis | Editorial | Article

    Do myositis-specific antibodies have an impact on the treatment of idiopathic inflammatory myopathies?

    Anti-MDA-5 positive ILD can be particularly refractory to all forms of therapy, and recent evidence suggests a rapid step up to second- and third-line therapies, including high dose intravenous glucocorticoids, cyclophosphamide, rituximab, cyclosporine and tacrolimus in various combinations can be lifesaving.

  6. 20-06-2019 | Systemic lupus erythematosus | Highlight | Article

    Systemic lupus erythematosus: Novel therapies and targeted treatments

    New therapeutic agents Voclosporin Voclosporin is a new potent calcineurin inhibitor with faster elimination and less variability in blood concentration compared with tacrolimus or cyclosporine.

  7. 10-06-2019 | Psoriatic arthritis | Feature | Article

    A closer look at guidelines for the management of PsA

    Indeed, for treatment-naïve patients with active PsA, the guidelines recommend first-line treatment with a TNF inhibitor over methotrexate, sulfasalazine, leflunomide, cyclosporine, and apremilast.

  8. 07-06-2019 | Rheumatoid arthritis | Case study | Article

    Tofacitinib in a patient with refractory severe rheumatoid arthritis

    She subsequently failed a number of conventional synthetic (cs)DMARDs including methotrexate, cyclosporine, azathioprine, and sulfasalazine due to a combination of nausea, anorexia, and malaise.

  9. 14-03-2019 | Kawasaki disease | News | Article

    IVIG–ciclosporin combination may improve coronary artery outcomes in Kawasaki disease

    Findings from the KAICA trial suggest that adding ciclosporin to intravenous immunoglobulin treatment may reduce the risk for coronary artery abnormalities among patients with Kawasaki disease.

  10. 27-09-2018 | Small-vessel vasculitis | Article

    Treatment of urticarial vasculitis: A systematic review

    Kolkhir P et al.  J Allergy Clin Immunol  2018. doi: 10.1016/j.jaci.2018.09.007

  11. 25-06-2018 | Rheumatoid arthritis | Review | Article

    Optimizing rheumatoid arthritis patients for surgery

    Sigmund A, Russell LA. Curr Rheumatol Rep 2018; 20: 48. doi: 10.1007/s11926-018-0757-x

  12. 18-06-2018 | Osteoporosis | Article

    Early use of alendronate as a protective factor against the development of glucocorticoid-induced bone loss in childhood-onset rheumatic diseases: A cross-sectional study

    Inoue, Y et al. Pediatr Rheumatol 2018; 16: 36. doi: 10.1186/s12969-018-0258-5

  13. 26-05-2018 | Sjögren’s syndrome | Review | Article

    Advances in the diagnosis and treatment of Sjogren’s syndrome

    Chen X, Wu H, Wei W. Clin Rheumatol 2018. doi: 10.1007/s10067-018-4153-8

  14. 17-05-2018 | Rheumatoid arthritis | Review | Article

    Cardiovascular system changes in rheumatoid arthritis patients with continued low disease activity

    Biskup M et al. Rheumatol Int 2018. doi: 10.1007/s00296-018-4053-x

  15. 15-05-2018 | Vasculitis | Article

    Efficacy of adalimumab and infliximab in recalcitrant retinal vasculitis inadequately responsive to other immunomodulatory therapies

    Fabiani C et al. Clin Rheumatol 2018. doi: 10.1007/s10067-018-4133-z

  16. 03-05-2018 | Systemic lupus erythematosus | Highlight | Teaser
    Journal article

    New trials in lupus and where are we going

    In this article, the authors review progress in the field of clinical trials for systemic lupus erythematosus [ read more ]. Thanou A, Merrill JT. Curr Rheumatol Rep 2018; 20: 34. doi: 10.1007/s11926-018-0745-1

  17. 03-05-2018 | Systemic lupus erythematosus | Review | Article

    New trials in lupus and where are we going

    In this article, the authors review progress in the field of clinical trials for systemic lupus erythematosus. Thanou A, Merrill JT. Curr Rheumatol Rep 2018; 20: 34. doi: 10.1007/s11926-018-0745-1

  18. 02-05-2018 | Granulomatosis with polyangiitis | Highlight | Teaser
    Practice tip: Case study

    Pyoderma gangrenosum-like ulcerations in granulomatosis with polyangiitis: Two cases and literature review

    The authors report two patients with ulcerative lesions resembling pyoderma gangrenosum that were the presenting sign of granulomatosis with polyangiitis and propose an approach to differentiate the two [read more ]. Genovese G et al. Rheumatol Int 2018; Advance online publication. doi: 10.1007/s00296-018-4035-z

  19. 02-05-2018 | Granulomatosis with polyangiitis | Case report | Article

    Pyoderma gangrenosum-like ulcerations in granulomatosis with polyangiitis: Two cases and literature review

    The authors report two patients with ulcerative lesions resembling pyoderma gangrenosum that were the presenting sign of granulomatosis with polyangiitis and propose an approach to differentiate the two. Genovese G et al. Rheumatol Int 2018; Advance online publication. doi: 10.1007/s00296-018-4035-z

  20. 19-12-2017 | Medications | Editorial | Article

    Managing antirheumatic medication in patients undergoing elective arthroplasty

    In patients with severe SLE, the current dose of mycophenolate mofetil, azathioprine, cyclosporine or tacrolimus can be continued during the surgical period in all patients undergoing THA or TKA.

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