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Inflammation 

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  1. 04-10-2021 | Axial spondyloarthritis | News | Article
    News in brief

    Inflammation tied to magnitude of secukinumab response in nonradiographic axSpA

    Treatment with secukinumab improves outcomes for people with nonradiographic axial spondyloarthritis across different subgroups, but those with objective signs of inflammation may experience the greatest benefits, suggests a post-hoc analysis of the PREVENT trial.

  2. 10-06-2021 | Rheumatoid arthritis | News | Article

    Inflammation not accurately reflected by tender joints in RA

    Tender joints in patients with rheumatoid arthritis may not be a suitable indicator of inflammation, study findings show.

  3. 03-06-2021 | EULAR 2021 | Conference coverage | Article

    Subset of RA patients with high disability, low inflammation identified

    Research presented at the EULAR 2021 Virtual Congress has identified a subgroup of patients with rheumatoid arthritis who have a high degree of disability despite low levels of inflammation.

  4. 06-05-2021 | COVID-19 | News | Article

    COVID-19: Control of inflammation ‘seems to be key’ in patients with rheumatic diseases

    Findings from the Euro-COVIMID study suggest that the seroprevalence and effects of SARS-CoV-2 infection in patients with rheumatic diseases are in line with those in the general population, and inflammation may be a risk factor for developing symptomatic COVID-19.

  5. 03-10-2019 | Rheumatoid arthritis | News | Article

    MRI inflammation may indicate RA patients most suited to combination therapy

    Patients with early rheumatoid arthritis and high levels of inflammation on hand–wrist magnetic resonance imaging derive greater benefit from combination therapy than those with low levels of inflammation, study findings indicate.

  6. 03-08-2018 | Psoriatic arthritis | News | Article

    Secukinumab may reduce synovial inflammation in PsA patients

    Treatment with the interleukin-17A inhibitor secukinumab is associated with a reduction in synovial inflammation among patients with psoriatic arthritis, results of the PSARTROS study suggest.

  7. 23-02-2018 | Psoriatic arthritis | Review | Article

    Psoriatic arthritis: Tissue-directed inflammation?

    Cafaro G, McInnes IB. Clin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4012-7

  8. 10-10-2018 | Systemic lupus erythematosus | News | Article

    Musculoskeletal inflammation in SLE not reliably identified with existing clinical instruments

    Existing classification systems for musculoskeletal symptoms in people with systemic lupus erythematosus fail to identify inflammation in a large proportion of those with synovitis, suggest findings reported in Rheumatology .

  9. 30-05-2018 | Enthesitis | Review | Article

    Enthesitis: Much more than focal insertion point inflammation

    Watad A et al. Curr Rheumatol Rep  2018; 20: 41. doi: 10.1007/s11926-018-0751-3

  10. 22-02-2018 | Ankylosing spondylitis | Article

    Ischemic heart disease and ankylosing spondylitis: Assessing the role of inflammation

    Vinker Shuster M et al. Clin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4037-y

  11. 04-10-2017 | Pathophysiology | Image

    The molecular mechanisms of low-grade inflammation in osteoarthritis

    This low-grade inflammation contributes to or mediates progressive cartilage loss, pain, and joint dysfunction.

  12. 26-09-2017 | Inflammation | Image

    IL-17 and IL-23 in chronic inflammation – Title slide

  13. 26-09-2017 | Inflammation | Image

    Key functions of IL-17 and its role in inflammation

    The effect of IL-17 on endothelial cells leads to inflammation and procoagulant activity.

  14. 04-08-2017 | Juvenile idiopathic arthritis | Review | Article

    Ultrasound imaging of synovial inflammation in juvenile idiopathic arthritis

    In this review, the authors provide an overview on the use of ultrasound to identify and monitor joint changes in patients with juvenile idiopathic arthritis. Chauvin NA, Doria AS. Pediatr Radiol 2017;47:1160–1170. doi:10.1007/s00247-017-3934-6

  15. 26-10-2017 | Image

    Synovial fluid and synovial membrane findings during the acute episodes of inflammation

  16. 03-05-2018 | Rheumatoid arthritis | Article

    Does psychological stress in patients with clinically suspect arthralgia associate with subclinical inflammation and progression to inflammatory arthritis?

    Boer AC et al. Arthritis Res Ther 2018; 20: 93. doi: 10.1186/s13075-018-1587-y

  17. 26-04-2018 | Ankylosing spondylitis | Article

    Tofacitinib is associated with attainment of the minimally important reduction in axial magnetic resonance imaging inflammation in ankylosing spondylitis patients

    Maksymowych WP et al. Rheumatology (Oxford) 2018; Advance online publication. doi: 10.1093/rheumatology/key104

  18. 18-03-2017 | Osteoporosis | Review | Article

    The epigenome at the crossroad between social factors, inflammation, and osteoporosis risk

    The authors explore the hypothesis that early life experiences may induce stress reactions and other responses that modify DNA methylation patterns and consequently influence the risk of osteoporosis in later life. Riancho JA, Brennan-Olsen SL. Clinic Rev Bone Miner Metab 2017;15:59-68. doi:10.1007/s12018-017-9229-5

  19. 13-07-2018 | Giant cell arteritis | News | Article
    News in brief

    Prolonged tocilizumab treatment needed to suppress GCA inflammation

    An analysis of inflammatory markers suggests that patients with giant cell arteritis who are treated with tocilizumab still have subclinical disease activity during early remission, but not after 1 year of treatment.

  20. 19-08-2016 | Osteoarthritis | Review | Article

    Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis

    The authors examine emerging evidence for a critical role of low-grade inflammation in the pathogenesis of osteoarthritis, and discuss current understanding of the underlying molecular mechanisms. Nat Rev Rheumatol 2016;12:580–592. doi:10.1038/nrrheum.2016.136

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