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Naproxen 

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  1. 11-11-2019 | Gout | News | Article

    Naproxen recommended over low-dose colchicine for gout flares

    Naproxen and low-dose colchicine are similarly effective in the reduction of pain associated with gout flares, but patients receiving colchicine tend to experience more side-effects, show results from the multicenter, open-label CONTACT trial.

  2. 08-06-2022 | EULAR 2022 | Conference coverage | Article

    NSAID suppression of axSpA spinal progression greatest with COX-2 selective inhibitors

    When ASAS NSAID Intake Score was also taken into account, the team found that receiving any NSAID was associated with more spinal progression, compared with no NSAID, and this was numerically higher in intervals with non-selective NSAIDs.

  3. 26-06-2018 | Juvenile idiopathic arthritis | Article

    A 6-month, multicenter, open-label study of fixed dose naproxen/esomeprazole in adolescent patients with juvenile idiopathic arthritis

    Primary objective was to evaluate the safety and tolerability of 3 fixed doses of naproxen/esomeprazole in juvenile idiopathic arthritis patients

  4. 22-06-2021 | Osteoarthritis | News | Article

    NSAID use, limited physical activity linked to knee OA progression risk

    Simic et al suggest that “NSAID users may represent people with greater symptoms, and thus more severe disease,” but note that “this theory is unlikely to fully explain the findings because high baseline pain was not associated with radiographic OA progression in the multivariable analysis.”

  5. 17-05-2021 | COVID-19 channel | News | Article

    NSAID use not linked to poor COVID-19 outcomes

    NSAID use is not associated with more severe disease among people admitted to hospital with COVID-19, including those with rheumatic diseases, show data from a large, prospective UK cohort study.

  6. 24-07-2020 | Osteoarthritis | Highlight | Teaser
    medwireNews top story

    CBT fails to match NSAID pain relief for knee osteoarthritis

    Placebo, followed by telephone-based cognitive behavioral therapy, does not meet noninferiority criteria compared with meloxicam for pain relief in patients with knee osteoarthritis, say US researchers.

  7. 24-07-2020 | Osteoarthritis | News | Article

    CBT fails to match NSAID pain relief for knee osteoarthritis

    The noninferiority randomized withdrawal trial included 364 veterans with knee OA who used an NSAID other than aspirin on most days for at least 3 months prior to enrolment.

  8. 01-07-2022 | Osteoarthritis | News | Article

    Vitamin K supplementation may warrant study in people with knee osteoarthritis

    The researchers note that their results remained “largely unchanged” after adjusting for NSAID use.

  9. 23-06-2022 | Treat-to-target | News | Article

    TNF inhibitor tapered T2T strategy feasible in PsA and axSpA

    There was also no significant difference in adverse event rates or quality of life between the two arms, but the initiation or escalation of concomitant medication was more common in the tapering group than in the no-tapering group, with a significant difference observed for NSAID use (54 vs 24%).

  10. 19-02-2020 | Osteoarthritis | News | Article
    approvalsWatch

    FDA approves over-the-counter diclofenac gel for osteoarthritis pain relief

    medwireNews : The US FDA has approved nonprescription diclofenac sodium topical gel, 1% for temporary pain relief in patients with osteoarthritis.

  11. 27-09-2019 | Ankylosing spondylitis | Highlight | Teaser
    medwireNews top story

    Continuous NSAID use linked to hypertension risk in ankylosing spondylitis

    Individuals with ankylosing spondylitis who continually use NSAIDs have an increased risk for hypertension relative to those who use the drugs less frequently, study findings indicate.

  12. 27-09-2019 | Ankylosing spondylitis | News | Article

    Continuous NSAID use linked to hypertension risk in ankylosing spondylitis

    Among the 129 patients with hypertension, 40% were continuous NSAID users and 60% were non-continuous or non-users.

  13. 12-02-2019 | Osteoarthritis | Highlight | Teaser
    medwireNews top story

    Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement

    Patients who are treated with ibuprofen alone experience comparable pain control in the first day after hip replacement to those give acetaminophen plus ibuprofen, findings from the PANSAID trial suggest.

  14. 12-02-2019 | Osteoarthritis | News | Article

    Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement

    Patients who are treated with ibuprofen alone experience comparable pain control in the first day after hip replacement to those give acetaminophen plus ibuprofen, findings from the PANSAID trial suggest.

  15. 16-01-2022 | Hyaluronic acid injection | Adis Journal Club | Article
    Advances in Therapy

    Hyaluronic Acid Therapy in Hip OA Does Not Perform Equally in Osteoarthritis Secondary to Juvenile Idiopathic Arthritis When Compared to Primary Osteoarthritis: A 2-Year Preliminary Evaluation

    Effectiveness (VAS and WOMAC), NSAID/analgesic consumption, tolerability, withdrawals and reason for discontinuation were collected at each time point.

  16. 17-07-2018 | Spondyloarthropathies | Highlight | Teaser
    medwireNews editor's pick

    Diclofenac linked to increased myocardial infarction risk in SpA patients

    Current use of the nonsteroidal anti-inflammatory drug diclofenac, but not of naproxen, is associated with a threefold increased risk for myocardial infarction among individuals with spondyloarthritis, according to recent findings.

  17. 02-05-2018 | Spondyloarthropathies | News | Article

    Diclofenac linked to increased myocardial infarction risk in SpA patients

    Current use of the nonsteroidal anti-inflammatory drug diclofenac, but not of naproxen, is associated with a threefold increased risk for myocardial infarction among individuals with spondyloarthritis, according to recent findings.

  18. 14-10-2021 | Osteoarthritis | News | Article

    Network meta-analysis compares analgesic regimens for osteoarthritis

    As reported in The BMJ , 74.5% of oral NSAID interventions showed statistical superiority over oral placebo, as did 33.3% of topical NSAID, 22.2% of opioid, and 33.3% of acetaminophen regimens.

  19. 30-08-2017 | Osteoarthritis | News | Article

    Ibuprofen associated with elevated blood pressure in patients with arthritis

    Patients with osteoarthritis or rheumatoid arthritis who take ibuprofen are more likely to experience an increase in systolic blood pressure than those taking celecoxib, results of the PRECISION-ABPM study suggest.

  20. 11-02-2021 | Osteoarthritis | News | Article

    Long-term data confirm risk to joints with tanezumab

    For the current safety study, patients with WOMAC Pain and Physical Function scores of 5 or more, a fair, poor, or very poor patient’s global assessment of OA (PGA‐OA), a history of inadequate pain relief with standard analgesics, and no history of other bone or joint conditions were randomly assigned to receive subcutaneous tanezumab 2.5 mg (n=1002) or 5.0 mg (n=998) every 8 weeks or to twice‐daily oral naproxen, celecoxib, or diclofenac (n=996), each for 56 weeks followed by a 24-week post‐treatment follow‐up period.

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