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48 search results for:

Polymyalgia rheumatica 

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  1. 22-09-2022 | Polymyalgia rheumatica | News | Article

    SEMAPHORE: Tocilizumab reduces disease activity in steroid-dependent polymyalgia rheumatica

    The IL-6 receptor inhibitor tocilizumab may significantly reduce disease activity and the amount of prednisone needed in people with glucocorticoid-dependent active polymyalgia rheumatica, suggest results from a phase 3 trial published in JAMA .

  2. 04-06-2022 | EULAR 2022 | Conference coverage | Article

    Sarilumab shows treatment promise in relapsing polymyalgia rheumatica

    Phase 3 SAPHYR study findings suggest that the IL-6 receptor inhibitor sarilumab with glucocorticoid taper is an efficacious treatment option for patients with steroid-resistant polymyalgia rheumatica.

  3. 02-06-2022 | EULAR 2022 | Conference coverage | Article
    News in brief

    Mortality risk may be ‘slightly increased’ in women with polymyalgia rheumatica

    Women with polymyalgia rheumatica may have a small increase in the risk for mortality relative to the general population, but not during the first 20 years after diagnosis, according to research presented at the EULAR 2022 Congress in Copenhagen, Denmark.

  4. 07-11-2021 | ACR 2021 | Conference coverage | Article

    Tocilizumab candidate for glucocorticoid-sparing agent in polymyalgia rheumatica

    Tocilizumab improves glucocorticoid-free remission rates, time to first relapse, and cumulative glucocorticoid dose versus placebo in people with polymyalgia rheumatica, show phase 2/3 study data presented at the ACR Convergence 2021 virtual meeting.

  5. 07-11-2021 | ACR 2021 | Conference coverage | Article

    High rates of severe COVID-19 in patients with vasculitis, polymyalgia rheumatica

    An analysis of data from the COVID-19 Global Rheumatology Alliance and EULAR COVID-19 registries suggests high rates of severe COVID-19 among people with primary systemic vasculitis or polymyalgia rheumatica.

  6. 30-09-2021 | Polymyalgia rheumatica | News | Article

    ‘Encouraging’ results for rituximab in patients with polymyalgia rheumatica

    Findings from the proof-of-concept BRIDGE-PMR study suggest that rituximab may be beneficial for  the treatment of polymyalgia rheumatica.

  7. 28-04-2021 | BSR 2021 | Conference coverage | Article

    Suboptimal prescribing of osteoporosis medications in people with polymyalgia rheumatica

    Less than half of patients with polymyalgia rheumatica are prescribed medications for osteoporosis, despite clinical guidelines recommending bone protection for those on long-term glucocorticoid treatment, research suggests.

  8. 20-11-2018 | Polymyalgia rheumatica | Article

    Comorbidities in polymyalgia rheumatica: A systematic review

    The objective of this study is to review systematically the existing literature on the comorbidities associated with polymyalgia rheumatica.

  9. 29-08-2018 | Giant cell arteritis | Article

    Additional costs of polymyalgia rheumatica with giant‐cell arteritis

    Mounié M et al. Arthritis Care Res 2018. doi: 10.1002/acr.23736

  10. 22-01-2018 | Polymyalgia rheumatica | News | Article

    Polymyalgia rheumatica, giant cell arteritis associated with increased fracture risk

    Patients with polymyalgia rheumatica or giant cell arteritis have an elevated risk for fracture compared with the general population, results of a UK database study suggest.

  11. 08-05-2016 | Polymyalgia rheumatica | Case report | Article

    Glucocorticoid-resistant polymyalgia rheumatica: Pretreatment characteristics and tocilizumab therapy

    This case-based review reports on characteristics and outcomes of glucocorticoid-resistant polymyalgia rheumatica, and the addition of tocilizumab with or without methotrexate.  Mori S, Koga Y.  Clin Rheumatol 2016; 35: 1367–1375. doi:10.1007/s10067-014-2650-y

  12. 15-07-2016 | Giant cell arteritis | Article

    The prevalence of giant cell arteritis and polymyalgia rheumatica in a UK primary care population

    UK clinical data were obtained and prevalence of giant cell arteritis and polymyalgia rheumatic were found to be higher in women than in men and in older age groups. Yates M et al. BMC Musculoskelet Disord 2016;17:285. doi:10.1186/s12891-016-1127-3

  13. 14-01-2016 | Quality of life | Review | Article

    Patient-reported outcomes in trials of patients with polymyalgia rheumatica: a systematic literature review

    The authors determined that although several patient-reported outcomes have been identified additional work is needed to obtain a better insight into the required outcomes that incorporate the patient’s perspective. Rheumatol Int 2016;36:897. doi:10.1007/s00296-015-3416-9

  14. 05-03-2021 | Glucocorticoids | News | Article

    High rates of long-term glucocorticoid use in people with GCA, PMR

    Real-world study results suggest that less than a third of patients with giant cell arteritis and/or polymyalgia rheumatica are able to discontinue glucocorticoid treatment for at least 6 months, and a substantial proportion remain on prednisone for at least 2 years.

  15. 07-11-2022 | Giant cell arteritis | News | Article

    Studies evaluate medications, biomarkers linked to GCA risk

    A similar pattern of results was seen for polymyalgia rheumatica (PMR).

  16. 01-09-2022 | Cardiovascular disease | News | Article

    CV risk reduction should be ‘an integral part’ of autoimmune disease management

    The HRs for other rheumatic diseases ranged from 1.47 for polymyalgia rheumatica to 2.08 for Sjögren’s syndrome, while those for other organ-specific conditions ranged from 1.38 for vitiligo to 2.36 for type 1 diabetes.

  17. 30-06-2022 | COVID-19 | News | Article

    VROOM trial: Pausing methotrexate doubles antibody response to COVID-19 booster vaccine

    The most common diagnosis was rheumatoid arthritis (51.2%), followed by psoriasis with arthritis (20.5%), and other diseases included spondyloarthritis, polymyalgia rheumatica, and systemic lupus erythematosus.

  18. 18-03-2022 | Polymyalgia rheumatica | News | Article

    Biomarkers may improve giant cell arteritis diagnosis

    Measuring erythrocyte sedimentation rate, angiopoietin-2/-1 ratio, and matrix metalloprotease-3 levels may help discriminate patients with isolated polymyalgia rheumatica from those with concomitant giant cell arteritis, research suggests.

  19. 12-05-2022 | COVID-19 | News | Article
    News in brief

    Study identifies risk factors for RMD flares following COVID-19 vaccination

    People with systemic lupus erythematosus (n=791) had a significant 51% higher risk for flare than those with rheumatoid arthritis (RA; n=1701) after adjustment for confounding factors, while patients with psoriatic arthritis (n=304) had a 95% increased risk and those with polymyalgia rheumatica (n=197) had a 94% increased risk.

  20. 07-02-2022 | Vitamin D | News | Article

    Vitamin D supplementation shows potential for reducing autoimmunity risk

    Findings from the VITAL trial suggest that vitamin D supplementation, with or without omega-3 fatty acids, may warrant further investigation as a strategy to reduce the risk for autoimmune diseases including rheumatoid arthritis and polymyalgia rheumatica.

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