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379 search results for:

Systemic lupus erythematosus 

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  1. 08-07-2022 | Systemic lupus erythematosus | Adis Journal Club | Article
    PharmacoEconomics

    Belimumab for Treating Active Autoantibody-Positive Systemic Lupus Erythematosus: An Evidence Review Group Perspective of a NICE Single Technology Appraisal

    Authors: Thomas Otten, Rob Riemsma, Ben Wijnen, Nigel Armstrong, Lisa Stirk, Caroline Gordon, Bram Ramaekers, Jos Kleijnen, Manuela Joore & Sabine Grimm Abstract As part of its Single Technology Appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer (GlaxoSmithKline [GSK]) of Benlysta (belimumab) to submit evidence regarding its clinical and cost effectiveness, for the review and possible extension of a previously conditionally approved intravenous formulation of belimumab for the treatment of active autoantibody-positive systemic lupus erythematosus (SLE).

  2. 08-10-2021 | Systemic lupus erythematosus | Adis Journal Club | Article
    Rheumatology and Therapy

    The Patient Experience of Fatigue in Systemic Lupus Erythematosus: A Conceptual Model

    Authors: Sophie Cleanthous, Sara Strzok, Birgit Haier, Stefan Cano & Thomas Morel Abstract Introduction Fatigue is frequently experienced in systemic lupus erythematosus (SLE) and is a key outcome in clinical research trials.

  3. 10-07-2021 | Adis Journal Club | Article
    Pediatric Drugs

    An Update on the Management of Childhood-Onset Systemic Lupus Erythematosus

    Authors: Vitor Cavalcanti Trindade, Magda Carneiro-Sampaio, Eloisa Bonfa & Clovis Artur Silva Abstract Childhood-onset systemic lupus erythematosus (cSLE) is a prototype of a multisystemic, inflammatory, heterogeneous autoimmune condition.

  4. 08-11-2020 | ACR 2020 | Conference coverage | Article

    BIIB059 improves active total joint count in systemic lupus erythematosus

    BIIB059, a monoclonal antibody that binds blood dendritic cell antigen 2 and inhibits interferon 1, improves total active joint count at 24 weeks in patients with systemic lupus erythematosus, findings from the LILAC trial show.

  5. 08-11-2020 | Systemic lupus erythematosus | Highlight | Teaser
    ACR Convergence 2020 news

    BIIB059 improves total active joint count in systemic lupus erythematosus

    BIIB059, a monoclonal antibody that binds blood dendritic cell antigen 2 and inhibits interferon 1, improves total active joint count at 24 weeks in patients with systemic lupus erythematosus, findings from the LILAC trial show.

  6. 13-08-2019 | Systemic lupus erythematosus | Highlight | Teaser
    Expert Opinion: Editorial

    Neuropsychiatric systemic lupus erythematosus: Issues in diagnosis and management

    Antigone Pieta, Dionysis Nikolopoulos, and Antonis Fanouriakis discuss the causes and management of neuropsychiatric systemic lupus erythematosus, and outline unmet needs in the diagnosis and treatment of this disease.

  7. 13-08-2019 | Systemic lupus erythematosus | Editorial | Article

    Neuropsychiatric systemic lupus erythematosus: Issues in diagnosis and management

    Antigone Pieta, Dionysis Nikolopoulos, and Antonis Fanouriakis discuss the causes and management of neuropsychiatric systemic lupus erythematosus, and outline unmet needs in the diagnosis and treatment of this disease.

  8. Efficacy and Safety of Intravenous Belimumab in Children with Systemic Lupus Erythematosus: An Across-Trial Comparison with the Adult Belimumab Studies

    Georgia World Congress Center, Atlanta, USA Presenting author:  Antonio Nino, USA What our Editorial Board said: This trial is of interest because it shows that belimumab is effective for children with systemic lupus erythematosus.

  9. 20-06-2019 | Systemic lupus erythematosus | Highlight | Teaser
    Expert Opinion: Editorial

    Systemic lupus erythematosus: Novel therapies and targeted treatments

    Andrea Fava and George Stojan review new strategies and agents for the treatment of systemic lupus erythematosus that have most recently showed promise in clinical trials.

  10. 20-06-2019 | Systemic lupus erythematosus | Highlight | Article

    Systemic lupus erythematosus: Novel therapies and targeted treatments

    Andrea Fava and George Stojan review new strategies and agents for the treatment of systemic lupus erythematosus that have most recently showed promise in clinical trials.

  11. 11-12-2018 | Systemic lupus erythematosus | Article

    New therapeutic strategies in systemic lupus erythematosus management

    Gatto M et al. Nat Rev Rheum 2018. doi: 10.1038/s41584-018-0133-2

  12. 01-06-2018 | Systemic lupus erythematosus | Article

    Monophasic disease course in systemic lupus erythematosus

    Tselios K et al. J Rheumatol 2018. doi: 10.3899/jrheum.171319

  13. 15-05-2018 | Systemic lupus erythematosus | Review | Article

    Monogenic systemic lupus erythematosus: Insights in pathophysiology

    Systemic lupus erythematosus (SLE) is a complex disease with different genetic, immunologic, and environmental factors contributing to the

  14. 17-10-2019 | Teaser
    ACR/ARP 2019 clinical trial recommendation

    Efficacy and Safety of Intravenous Belimumab in Children with Systemic Lupus Erythematosus: An Across-Trial Comparison with the Adult Belimumab Studies

    Wednesday,   November 13, 09:00–09:15. Georgia World Congress Center, Atlanta, USA Presenting author:  Antonio Nino, USA What our Editorial Board said: This trial is of interest because it shows that belimumab is effective for children with systemic lupus erythematosus. The implication is that belimumab can be used in the pediatric population just as it is for adults. –  Sangeeta Sule, USA

  15. 13-06-2018 | Systemic lupus erythematosus | Article

    Lupus retinopathy: A marker of active systemic lupus erythematosus

    Retinopathy in the context of systemic lupus erythematosus (SLE) is associated with severe disease and poorer prognosis.

  16. 27-06-2018 | Systemic lupus erythematosus | Highlight | Teaser
    Journal article

    Acquired angioedema in juvenile systemic lupus erythematosus: case-based review

    Tekin et al. report the case of a previously healthy 16-year-old girl with an acquired angioedema as a rare and initial presentation of systemic lupus erythematosus, and review the related literature [ read more ]. Tekin ZE, Yener GO, Yüksel S. Rheumatol Int 2018. doi: 10.1007/s00296-018-4088-z

  17. 21-02-2018 | Systemic lupus erythematosus | Review | Article

    Pathogenesis of skin injury of systemic lupus erythematosus

    The second most common clinical expression in lupus patients is skin damage that the pathogenesis remains unclear.

  18. 15-07-2018 | Epidemiology | Article

    Epidemiology and survival of systemic sclerosis-systemic lupus erythematosus overlap syndrome

    Alharbi S et al. J Rheumatol 2018. doi: 10.3899/jrheum.170953

  19. 28-07-2018 | Systemic lupus erythematosus | Review | Article

    Artemisinins: A promising new treatment for systemic lupus erythematosus. A descriptive review

    In this review, the authors evaluate the therapeutic properties and potential mechanisms of artemisinins for the treatment of systemic lupus

  20. 01-09-2018 | Systemic lupus erythematosus | Article

    Canadian Rheumatology Association recommendations for the assessment and monitoring of systemic lupus erythematosus

    Keeling SO et al. J Rheumatol 2018. doi: 10.3899/jrheum.171459

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