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Voclosporin 

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  1. 01-08-2022 | Lupus nephritis | News | Article
    approvalsWatch

    Voclosporin set for EMA approval for lupus nephritis

    The EMA recommends that voclosporin should be used in combination with mycophenolate mofetil for treating active class III, IV, or V lupus nephritis in adults.

  2. 10-11-2021 | ACR 2021 | Conference coverage | Article
    News in brief

    ​​​​​​​AURORA 2 shows enduring proteinuria benefits with voclosporin in lupus nephritis

    Voclosporin has a sustained proteinuria-reducing effect in patients with lupus nephritis, suggests an interim analysis of the AURORA 2 study.

  3. 18-05-2021 | Lupus nephritis | News | Article

    AURORA 1: Voclosporin improves renal outcomes in patients with lupus nephritis

    Adding the calcineurin inhibitor voclosporin to background immunosuppressive therapy improves renal response rates among people with lupus nephritis, show phase 3 trial results published in The Lancet .

  4. 08-11-2021 | ACR 2021 | Conference coverage | Article

    Add-on treatment for lupus nephritis: Should belimumab or voclosporin be used first?

    “This has been a controversial point for belimumab efficacy,” unlike in the voclosporin trial, in which the between-group difference for voclosporin versus placebo did reach statistical significance in the 45 Black patients, Petri conceded.

  5. 02-02-2021 | Lupus nephritis | News | Article
    approvalsWatch

    Voclosporin approved for lupus nephritis in the USA

    medwireNews : The US FDA has approved voclosporin, a calcineurin inhibitor, as the first oral treatment option for active lupus nephritis.

  6. 24-05-2021 | ACR 2021 | Teaser

    ACR Convergence 2021 highlights

    3–9 November: Keep up with the latest news and interviews from the conference.

  7. 10-07-2021 | Adis Journal Club | Article
    Pediatric Drugs

    An Update on the Management of Childhood-Onset Systemic Lupus Erythematosus

    Calcineurin inhibitors (cyclosporine, tacrolimus, voclosporin) appear to be a good option for cSLE patients with lupus nephritis.

  8. 20-06-2019 | Systemic lupus erythematosus | Highlight | Article

    Systemic lupus erythematosus: Novel therapies and targeted treatments

    Glomerular filtration rate decreased with voclosporin.

  9. 29-01-2019 | Lupus nephritis | Editorial | Article

    Emerging therapies for lupus nephritis

    The AURA-LV phase II trial (NCT02141672), which compared two dosing regimens of voclosporin to placebo on background steroids and MMF, generated a higher response rate with low dose voclosporin compared with placebo (49.4% vs 23.9% at 48 weeks).

  10. 20-06-2019 | Systemic lupus erythematosus | Highlight | Teaser
    Expert Opinion: Editorial

    Systemic lupus erythematosus: Novel therapies and targeted treatments

    Andrea Fava and George Stojan review new strategies and agents for the treatment of systemic lupus erythematosus that have most recently showed promise in clinical trials.

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