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Vasculitis

Highlights

MRI of brain

20-08-2020 | Giant cell arteritis | Highlight | News

Meta-analysis highlights clinical, laboratory features suggestive of GCA

The authors of a systematic review and meta-analysis have identified a number of clinical and laboratory features that should be assessed when investigating patients with suspected giant cell arteritis.

IV drip 2

01-06-2020 | ANCA-associated vasculitis | Highlight | News

MAINRITSAN3: Prolonged rituximab recommended for maintenance of remission in AAV

Long-term maintenance treatment with biannual rituximab infusions increases the likelihood of remaining in remission among people with antineutrophil cytoplasmic antibody-associated vasculitis, suggest findings from the MAINRITSAN3 trial.

New Content Item

26-02-2020 | Glucocorticoids | Highlight | News

Metformin could mitigate glucocorticoid-related complications

Findings from a proof-of-concept phase 2 study suggest that treatment with the antidiabetes drug metformin could help minimize some metabolic complications and improve clinical outcomes for patients taking systemic glucocorticoid therapy.

Ultrasound

25-10-2018 | Giant cell arteritis | ACR/ARHP 2018 | News

Ultrasound shows potential for early diagnosis of large vessel giant cell arteritis

Vascular ultrasound could be a contender as a first-line imaging test for diagnosing large vessel giant cell arteritis, suggests research.

PET/CT scan (symbolic image with model)

22-10-2018 | Giant cell arteritis | ACR/ARHP 2018 | News

Support for PET imaging in early giant cell arteritis diagnosis

Imaging with a combined positron emission tomography and computed tomography scanner shows good accuracy for diagnosing giant cell arteritis versus the gold-standard temporal artery biopsy.

31-08-2018 | Immune checkpoint inhibitor-induced rheumatic disease | Review | Article

Rheumatic immune-related adverse events from cancer immunotherapy

Calabrese LH, Calabrese C, Cappelli LC. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0074-9

14-08-2018 | ANCA-associated vasculitis | Review | Article

B cell therapy in ANCA-associated vasculitis: Current and emerging treatment options

McClure M et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0065-x

Whole-body CT (pelvis region) showing destruction and sclerosis of the left hip bones

27-07-2018 | Bone diseases | Case report | Article

Unusual case of chronic recurrent multifocal osteomyelitis

The authors present a rare case of sporadic chronic recurrent multifocal osteomyelitis in which the patient eventually developed cytoplasmic anti-neutrophil cytoplasmic antibodies-associated renal vasculitis and hyperparathyroidism.

Snipaitiene A et al. Pediatr Rheumatol 2018; 16: 49. doi: 10.1186/s12969-018-0267-4

Elderly person taking pills (symbolic image with model)

20-07-2018 | Granulomatosis with polyangiitis | Editorial | Article

The ongoing evolution of remission maintenance strategies for granulomatosis with polyangiitis

Eric J Gapud and Philip Seo summarize the key milestones in management of severe granulomatosis with polyangiitis, and evaluate the possibility of long-term reduced intensity or drug-free remission for some patients.

Syringe

19-06-2018 | Vasculitis | Article

Vasculitis associated with immune checkpoint inhibitors: A systematic review

Daxini A, Cronin K, Sreih AG. Clin Rheumatol 2018. doi: 10.1007/s10067-018-4177-0

Vasculitis with granulomatous features of a small artery characterized by thickness of the walls, angiocentric fibrosis with intramural and extramural infiltration made by lymphocytes, neutrophils and histiocytes

02-05-2018 | Granulomatosis with polyangiitis | Case report | Article

Pyoderma gangrenosum-like ulcerations in granulomatosis with polyangiitis: Two cases and literature review

The authors report two patients with ulcerative lesions resembling pyoderma gangrenosum that were the presenting sign of granulomatosis with polyangiitis and propose an approach to differentiate the two.

Genovese G et al. Rheumatol Int 2018; Advance online publication. doi: 10.1007/s00296-018-4035-z

Osteoporosis (illustration)

12-04-2018 | Osteoporosis | Article | News

Trial results back denosumab as a treatment option for glucocorticoid-induced osteoporosis

Patients with glucocorticoid-induced osteoporosis who are treated with denosumab have greater improvements in bone mineral density than those treated with risedronate, phase III trial results suggest.

Pregnant woman with doctor (symbolic image with model)

17-01-2018 | Takayasu arteritis | Case report | Article

Takayasu arteritis a cause of hypertensive disorder of pregnancy: A case report

The authors present a case of 21-year-old Mexican woman of Mestizo descent with chronic hypertension diagnosed since she was 15-years old who presented severe hypertension during pregnancy (early second trimester).

Lumbreras-Marquez J et al. J Med Case Reports 2018; 12: 12. doi: 10.1186/s13256-017-1534-6