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Vasculitis

Pathophysiology

Rituximab and rheumatology practice in the COVID-19 era

Rituximab and rheumatology practice in the COVID-19 era

How can rheumatologists respond to the challenges associated with rituximab use during the pandemic?

Anifrolumab for the treatment of lupus

Anifrolumab for the treatment of SLE

Perspective on the approval of anifrolumab and the importance of endpoints in lupus trials.

New additions to the Adis Journal Club

Adis Journal Club

A monthly selection of topical peer-reviewed articles from the Adis journals, curated by the editors.

JAK inhibitor safety

Data summary, expert discussion, & research news on the potential risks associated with JAK inhibitors.

ACR Convergence 2021 highlights

ACR Convergence 2021

3–9 November: Keep up with the latest news and interviews from the conference.

Febuxostat and cardiovascular risk in people with gout

Febuxostat and cardiovascular risk in people with gout

How will the FAST trial results impact regulatory guidance & clinical practice?

Telemedicine in rheumatology

Telemedicine in rheumatology: COVID-19 and beyond

Experts discuss the increasing use of telemedicine in rheumatology during the COVID-19 pandemic.

Get ready for ACR Convergence 2020

ACR Convergence 2020

5 – 9 November: Preview the conference with session recommendations and updates on upcoming coverage.

08-05-2018 | Kawasaki disease | Review | Article

Circulating adipokines are associated with Kawasaki disease

Zhang X et al. Pediatr Rheumatol 2018; 16: 33. doi: 10.1186/s12969-018-0243-z

04-04-2018 | Takayasu arteritis | Review | Article

Takayasu arteritis: Advanced understanding is leading to new horizons

Tombetti E, Mason JC. Rheumatology (Oxford) 2018; Advance online publication. doi: 10.1093/rheumatology/key040

02-04-2018 | Giant cell arteritis | Review | Article

Recent advances in giant cell arteritis

Guevara M, Kollipara CS. Curr Rheumatol Rep 2018; 20: 25. doi: 10.1007/s11926-018-0737-1

07-03-2018 | Pathophysiology | Review | Article

Role of human leukocyte antigens (HLA) in autoimmune diseases

Bodis G, Toth V, Schwarting A. Rheumatol Ther 2018; Advance online publication. doi: 10.1007/s40744-018-0100-z

13-02-2018 | Immunoglobulin A vasculitis | Review | Article

IgA vasculitis in adults

Moran SM, Reich HN. Curr Treat Options in Rheum 2018; 4: 119–132. doi: 10.1007/s40674-018-0088-0

09-02-2018 | Kawasaki disease | Article

The association between oxidative stress and endothelial dysfunction in early childhood patients with Kawasaki disease

Ishikawa T, Seki K. BMC Cardiovasc Disord 2018; 18: 30. doi: 10.1186/s12872-018-0765-9

Behçet syndrome: a contemporary view

Behçet syndrome: a contemporary view

In this review, the authors discuss the emerging, most-recent evidence on the etiology, manifestations and epidemiology of Behçet syndrome [read more].
Nat Rev Rheumatol 2018; 14: 107–119. doi: 10.1038/nrrheum.2017.208

07-08-2017 | Vasculitis | Review | Article

Vasculitis update: Pathogenesis and biomarkers

Brogan & Eleftheriou summarize recent advances in the understanding of the pathophysiology of primary systemic vasculitides and the potential role of novel biomarkers discovered in that context. 

Brogan P, Eleftheriou D. Pediatr Nephrol 2017. doi:10.1007/s00467-017-3597-4

03-03-2017 | Vasculitis | Review | Article

Clinical and pathological evolution of giant cell arteritis: a prospective study of follow-up temporal artery biopsies in 40 treated patients

This prospective study showed that responses to glucocorticoids were frequently discordant, supporting the hypothesis that vascular inflammation may still persist after treatment. 

Mod Pathol 2017;30(6):788-796. doi:10.1038/modpathol.2017.10

11-04-2016 | Vasculitis | Review | Article

Giant cell arteritis: From pathogenesis to therapeutic management

The authors propose that it has been difficult to identify clinically meaningful effects of targeted biologic therapies in giant cell arteritis, and discuss the possible multiple pathogenic reasons behind this. 

Watanabe R et al. Curr Treat Options in Rheum 2016;2:126. doi:10.1007/s40674-016-0043-x

Figure 1

21-06-2015 | Vasculitis | Review | Article

Epigenetics and vasculitis: A comprehensive review

Recognising that although epigenetic studies in vasculitis are still in their infancy, the authors review the most recent data on these mechanisms to better understand the pathogenesis of this disease.

Renauer P, Coit P, & Sawalha AH. Clinic Rev Allerg Immunol 2016;50:357. doi:10.1007/s12016-015-8495-6