Abstract
Episcleritis is a benign disease that presents as an uncomfortable red eye, sometimes with tearing and mild photophobia. Pain, if any, is mild and localized to the eye. Episcleritis rarely causes significant adverse ocular sequelae and is infrequently associated with systemic disease. Unlike episcleritis, scleritis is a severe inflammatory disease that can be progressively destructive, sometimes leading to loss of vision or loss of the eye. It presents with deep, severe pain, often radiating to the forehead, the jaw, and the sinuses. Scleritis is often associated not only with ocular complications (keratitis, uveitis, glaucoma, and cataract if anterior or fundus abnormalities if posterior), but also with immune-mediated systemic diseases, some of them potentially lethal.
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de la Maza, M.S., Tauber, J., Foster, C.S. (2012). Clinical Considerations of Episcleritis and Scleritis. In: The Sclera. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6502-8_4
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