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Support for further investigation of metformin in people with osteoarthritis

Anti-dsDNA antibodies have potential to guide targeted therapy use in SLE

EMA restricts JAK inhibitor use in high-risk patient groups

Baricitinib linked to increased risk for VTE

Similar reduction in CV risk with different add-on RA treatments

CA72-4 independently associated with gout flare risk in people initiating ULT

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IN FOCUS | JAK inhibitors

18-10-2022 | Psoriatic arthritis | News

Support for JAK inhibitors as ‘drug of choice’ for patients with PsA and significant joint disease

JAK inhibitors show promise for the treatment of moderate-to-severe psoriasis and psoriatic arthritis, finds a systematic review and meta-analysis of more than 6000 patients.

EMA restricts JAK inhibitor use in high-risk patient groups

Baricitinib linked to increased risk for VTE

JUVE-BASIS: Support for baricitinib in juvenile arthritis

ASAS, EULAR issue updated recommendations on axSpA management

Support for JAK inhibitors as ‘drug of choice’ for patients with PsA and significant joint disease

Study identifies sex differences in RA remission rates

IN FOCUS | COVID-19 & rheumatic disease

24-10-2022 | COVID-19 | News

Prophylactic antivirals may help prevent symptomatic COVID-19 in rituximab-treated patients

Pre-exposure prophylaxis with tixagevimab and cilgavimab may be an effective strategy to prevent symptomatic SARS-CoV-2 infection among people with rheumatic diseases treated with rituximab, suggest findings from a real-world study.

IN FOCUS | Inflammatory arthritis

07-12-2022 | Rheumatoid arthritis | News

Similar reduction in CV risk with different add-on RA treatments

Among patients with active rheumatoid arthritis, adding tumor necrosis factor inhibitors to methotrexate is associated with a similar reduction in vascular inflammation to that seen with add-on sulfasalazine plus hydroxychloroquine, suggest findings from a randomized controlled trial.

Similar reduction in CV risk with different add-on RA treatments

CA72-4 independently associated with gout flare risk in people initiating ULT

The metabolic syndrome may influence the risk for gout

Treatment goals in late-onset RA should match those for younger patients

A Great Debate: To treat or not to treat in pre-RA?

Secukinumab comparable to adalimumab biosimilar in axSpA

IN FOCUS | Gout and crystal arthropathies

04-08-2022 | Gout | News

Gout flares linked to temporary increase in cardiovascular risk

Gout flares are associated with an increased risk for cardiovascular events in the following 120 days, study findings suggest.

CA72-4 independently associated with gout flare risk in people initiating ULT

The metabolic syndrome may influence the risk for gout

SGLT2 inhibitors linked to lower gout risk than DPP-4 inhibitors

Local environment impacts recurrent hospitalization risk in rheumatic disease

Gout risk factor prevalence may explain increased rates among Black Americans

Gout flares linked to temporary increase in cardiovascular risk

IN FOCUS | Lupus

14-11-2022 | ACR 2022 | Conference coverage | News

Phase 3 trial supports add-on telitacicept for SLE

Addition of the recombinant fusion protein telitacicept to standard care may reduce disease activity and is well tolerated in people with systemic lupus erythematosus, research suggests.

Anti-dsDNA antibodies have potential to guide targeted therapy use in SLE

Phase 3 trial supports add-on telitacicept for SLE

Achieving LLDAS tied to reduced mortality risk in SLE

Dapagliflozin may warrant further investigation for SLE

Reduced-dose hydroxychloroquine linked to higher flare risk in SLE

Local environment impacts recurrent hospitalization risk in rheumatic disease

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