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Rheumatoid arthritis

Dual TNF, IL-17A inhibition no better than adalimumab for the treatment of inflammatory arthritis

Antibodies

Results of two phase II trials published in Arthritis & Rheumatology suggest that ABT-122, an antibody targeting TNF and IL-17A, has a similar efficacy and safety profile to that of adalimumab in patients with rheumatoid arthritis and psoriatic arthritis.

Gender differences in axial spondyloarthritis: Women are not so lucky

New Content Item

Rusman T, van Vollenhoven RF, van der Horst-Bruinsma IE. Curr Rheumatol Rep 2018; 20: 35. doi: 10.1007/s11926-018-0744-2

Comorbid fibromyalgia common in patients with inflammatory arthritis

Doctor and patient

Results of a systematic review and meta-analysis suggest that a substantial proportion of patients with chronic inflammatory arthritis have concomitant fibromyalgia, which may influence measures of disease activity.

HBV infection may compromise treatment response in patients with RA

Hepatitis

Chronic hepatitis B virus infection is associated with poor response to treatment among patients with rheumatoid arthritis, study results suggest.

Trial results back denosumab as a treatment option for glucocorticoid-induced osteoporosis

New Content Item

Patients with glucocorticoid-induced osteoporosis who are treated with denosumab have greater improvements in bone mineral density than those treated with risedronate, phase III trial results suggest.

SIRROUND-H: Sirukumab, adalimumab may have similar efficacy in RA patients

Injection

Patients with rheumatoid arthritis who are treated with the interleukin-6 inhibitor sirukumab experience comparable benefits to those given adalimumab, results of the phase III SIRROUND-H trial suggest.

Antidrug antibodies may contribute to TNF inhibitor failure in arthritis patients

Antibodies

The development of antidrug antibodies against adalimumab or infliximab, but not etanercept, may play a role in the development of secondary treatment failure among patients with rheumatoid arthritis or spondyloarthritis, researchers report.

Menopause associated with physical decline in women with RA

Arthritis hands

Postmenopausal women with rheumatoid arthritis may experience a greater decline in physical functioning than their premenopausal counterparts, results of a US study suggest.

09-02-2018 | Rheumatoid arthritis | Feature | News

Should treatment be tapered in patients with RA?

medwireNews speaks to Vivian Bykerk about whether treatment should be tapered in patients with rheumatoid arthritis.

19-12-2017 | Medications | Editorial | Article

Managing antirheumatic medication in patients undergoing elective arthroplasty

Editorial Board member Oliver FitzGerald reviews the recent guideline for the perioperative management of antirheumatic medication in patients with rheumatic diseases undergoing elective total hip or total knee arthroplasty.

24-10-2017 | Rheumatoid arthritis | Editorial | Article

Demise of the triple

Editorial Board member Marc Cohen reviews the use of triple therapy for the treatment of rheumatoid arthritis, and discusses the possible reasons for its underutilization compared with biologic therapies.

Themed collections

29-01-2018 | Biosimilars | Themed collection | Collection

Biosimilars

This content collection provides an overview of biosimilars in rheumatology, with a focus on switching between biosimilars and their originators, as well as discussions on safety and monitoring/pharmacovigilance, and a look at the pharmacoeconomics of biosimilars.

Journal articles and book chapters

Guidelines

A convenient single access point, providing rheumatology professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Images and illustrations

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for rheumatology healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within rheumatology management, as recommended by our Editorial Board.

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