Abstract
Summary
In Korean, atypical subtrochanteric fractures (ASF) were rare. Higher BMI and use of bisphosphonate were significant risk factors of ASF.
Introduction
Recently, ASF have been reported to increase among patients on bisphosphonate. However, the incidence of ASF and the association between ASF and bisphosphonate use have not been well defined in Asian population. Our purposes are (1) to estimate the proportion of ASF among Korean patients with proximal femur fracture and (2) to determine the associated risk factors of ASF in the Korean patients.
Methods
We conducted a multicenter (16 academic hospitals), prospective Korean hip fracture study on hip fracture in a cohort of patients aged 50 years or older from South Korea between July 2014 and May 2016. As a part of Korean hip fracture study, primary analysis examined the proportion of ASF among proximal femur fracture. To identify ASF, according to the definition by ASBMR task force, all radiographs of subtrochanteric fracture were reviewed. Associated risk factors for occurrence of ASF were also evaluated by using multivariable logistic regression analysis.
Results
Among 1361 patients with proximal femoral fractures due to low-energy trauma, 17 fractures (1.2%) were identified as ASF. Higher BMI and use of bisphosphonate before injury were independent risk factors of ASF.
Conclusion
In Korean, ASF were rare. Higher BMI and use of bisphosphonate were significant risk factors of ASF.
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Acknowledgements
This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health and Welfare, Republic of Korea (grant number: HC15C1189 and HI10C2020).
All authors were responsible for the drafting of the manuscript and revising the contents, and all authors approved the final version of the manuscript.
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This study was conducted according to the Declaration of Helsinki. Approval was obtained from the institutional review boards at each site.
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Lee, YK., Kim, TY., Ha, YC. et al. Atypical subtrochanteric fractures in Korean hip fracture study. Osteoporos Int 28, 2853–2858 (2017). https://doi.org/10.1007/s00198-017-4112-2
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DOI: https://doi.org/10.1007/s00198-017-4112-2