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Questionnaire survey evaluating disease-related knowledge for 149 primary gout patients and 184 doctors in South China

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Abstract

This study aims to investigate the disease-related knowledge of gout patients and doctors in south China and to identify the important targets of education for patients and doctors. A cross-section survey of 154 primary gout patients and 185 doctors who may see gout patients was conducted with a modified questionnaire with ten items of gout-related knowledge. The participants were considered to have gout-related knowledge if he or she correctly answered seven or more items. One hundred and forty-nine valid questionnaires from patients, 33 from rheumatology physicians, and 151 from non-rheumatology doctors were collected for statistical analysis. The mean correctly answered items of three groups were 6.6 ± 2.2, 9.6 ± 0.53, and 8.0 ± 1.4, with rate of being considered to have knowledge about gout 51.7, 100, and 90.1 %, respectively (P < 0.05). The correct answer rate for each particular item was over 80 % in the rheumatology physician group. Patients or non-rheumatology doctors knew the optimal serum uric acid (sUA) level (48.3 vs 55.6 %), the need to take lifelong urate-lowering drugs (29.5 vs 43.6 %), that allopurinol is a urate-lowering drug (55.7 vs 76.0 %), and how to prevent attacks induced by urate-lowering therapy (ULT) (60.4 vs 74.0 %). Logistic regression showed that higher education predicted which patients had gout-related knowledge. Both the gout patients and non-rheumatology doctors in south China had poor knowledge on ULT. Since many gout patients do not see rheumatologists, our data suggest that further education should focus on patients and non-rheumatologists and emphasize the use of urate-lowering drugs, treatment duration, the target sUA level, and prophylaxis against acute attacks.

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References

  1. Fang W, Zeng X, Li M, Chen LX, Schumacher HJ, Zhang F (2006) The management of gout at an academic healthcare center in Beijing: a physician survey. J Rheumatol 33:2041–2049

    PubMed  Google Scholar 

  2. Yu JW, Yang TG, Diao WX, Cai XQ, Li T, Zhong H et al (2010) Epidemiological study on hyperuricemia and gout in Foshan areas, Guangdong Province. Zhonghua Liu Xing Bing Xue Za Zhi 31:860–862

    PubMed  CAS  Google Scholar 

  3. Zeng Q, Wang Q, Chen R, Xiao Z, Huang S, Xu J (2003) Primary gout in Shantou: a clinical and epidemiological study. Chin Med J (Engl) 116:66–69

    Google Scholar 

  4. Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440:237–241

    Article  PubMed  CAS  Google Scholar 

  5. Zhang W, Doherty M, Bardin T, Pascual E, Barskova V, Conaghan P et al (2006) EULAR evidence based recommendations for gout. Part II: management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 65:1312–1324

    Article  PubMed  CAS  Google Scholar 

  6. Zhang W, Doherty M, Pascual E, Bardin T, Barskova V, Conaghan P et al (2006) EULAR evidence based recommendations for gout. Part I: diagnosis. Report of a task force of the Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 65:1301–1311

    Article  PubMed  CAS  Google Scholar 

  7. Chinese Rheumatology Association (2011) The diagnosis and treatment guideline of primary gout. Chin J Rheumatol 15:410–413

    Google Scholar 

  8. Doherty M, Jansen TL, Nuki G, Pascual E, Perez-Ruiz F, Punzi L et al (2012) Gout: why is this curable disease so seldom cured? Ann Rheum Dis 71:1765–1770

    Article  PubMed  Google Scholar 

  9. Brook RA, Forsythe A, Smeeding JE, Lawrence EN (2010) Chronic gout: epidemiology, disease progression, treatment and disease burden. Curr Med Res Opin 26:2813–2821

    Article  PubMed  Google Scholar 

  10. Mikuls TR (2007) Quality of care in gout: from measurement to improvement. Clin Exp Rheumatol 25:114–119

    PubMed  CAS  Google Scholar 

  11. Becker MA, Schumacher HR, Benjamin KL, Gorevic P, Greenwald M, Fessel J et al (2009) Quality of life and disability in patients with treatment-failure gout. J Rheumatol 36:1041–1048

    Article  PubMed  Google Scholar 

  12. Taylor WJ, Colvine K, Gregory K, Collis J, McQueen FM, Dalbeth N (2008) The Health Assessment Questionnaire Disability Index is a valid measure of physical function in gout. Clin Exp Rheumatol 26:620–626

    PubMed  CAS  Google Scholar 

  13. Rees F, Jenkins W, Doherty M (2013) Patients with gout adhere to curative treatment if informed appropriately: proof-of-concept observational study. Ann Rheum Dis 72:826–830

    Article  PubMed  Google Scholar 

  14. Khanna D, Fitzgerald JD, Khanna PP, Bae S, Singh MK, Neogi T et al (2012) 2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care Res (Hoboken) 64:1431–1446

    Article  CAS  Google Scholar 

  15. Zhang LY, Schumacher HR, Su HH, Dai L, Dinnella J, Baker JF et al (2011) Development and evaluation of a survey of gout patients concerning their knowledge about gout. J Clin Rheumatol 17:242–248

    Article  PubMed  CAS  Google Scholar 

  16. Wallace SL, Robinson H, Masi AT, Decker JL, McCarty DJ, Yu TF (1977) Preliminary criteria for the classification of the acute arthritis of primary gout. Arthritis Rheum 20:895–900

    Article  PubMed  CAS  Google Scholar 

  17. National Kidney Foundation (2002) K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 39:S1–S266

    Google Scholar 

  18. Ma YC, Zuo L, Chen JH, Luo Q, Yu XQ, Li Y et al (2006) Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease. J Am Soc Nephrol 17:2937–2944

    Article  PubMed  Google Scholar 

  19. Spencer K, Carr A, Doherty M (2012) Patient and provider barriers to effective management of gout in general practice: a qualitative study. Ann Rheum Dis 71(9):1490–1495

    Article  PubMed  Google Scholar 

  20. Martini N, Bryant L, Te KL, Aho L, Chan R, Miao J et al (2012) Living with gout in New Zealand: an exploratory study into people's knowledge about the disease and its treatment. J Clin Rheumatol 18:125–129

    Article  PubMed  Google Scholar 

  21. Yamanaka H, Togashi R, Hakoda M, Terai C, Kashiwazaki S, Dan T et al (1998) Optimal range of serum urate concentrations to minimize risk of gouty attacks during anti-hyperuricemic treatment. Adv Exp Med Biol 431:13–18

    Article  PubMed  CAS  Google Scholar 

  22. Pascual E, Sivera F (2007) Time required for disappearance of urate crystals from synovial fluid after successful hypouricaemic treatment relates to the duration of gout. Ann Rheum Dis 66:1056–1058

    Article  PubMed  CAS  Google Scholar 

  23. Perez-Ruiz F, Calabozo M, Pijoan JI, Herrero-Beites AM, Ruibal A (2002) Effect of urate-lowering therapy on the velocity of size reduction of tophi in chronic gout. Arthritis Rheum 47:356–360

    Article  PubMed  CAS  Google Scholar 

  24. Becker MA, Schumacher HJ, Wortmann RL, MacDonald PA, Eustace D, Palo WA et al (2005) Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med 353:2450–2461

    Article  PubMed  CAS  Google Scholar 

  25. Edwards NL (2011) Quality of care in patients with gout: why is management suboptimal and what can be done about it? Curr Rheumatol Rep 13:154–159

    Article  PubMed  Google Scholar 

  26. Harrold LR, Mazor KM, Velten S, Ockene IS, Yood RA (2010) Patients and providers view gout differently: a qualitative study. Chronic Illn 6:263–271

    Article  PubMed  Google Scholar 

  27. Singh JA, Hodges JS, Toscano JP, Asch SM (2007) Quality of care for gout in the US needs improvement. Arthritis Rheum 57:822–829

    Article  PubMed  Google Scholar 

  28. Weaver AL, Cheh MA, Kennison RH (2008) How PCP education can impact gout management: the gout essentials. J Clin Rheumatol 14:S42–S46

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Rheumatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107# Yan Jiang West Road, Guangzhou, 510120, China

    Qian-Hua Li, Lie Dai, Zhao-Xia Li, Chan-Juan Zou, Yan-Hua Li & Yin-Qian Mo

  2. Department of Rheumatology, Pan Yu Central Hospital, Guangzhou, China

    Hai-Jun Liu & Xia Ou-Yang

  3. Department of Rheumatology, The First People’s Hospital of Shun De, Foshan, China

    Meng Lu

  4. Department of Rheumatology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China

    Ting Li

  5. Division of Rheumatology, VA Medical Center, University of Pennsylvania, Philadelphia, PA, USA

    H. Ralph Schumacher

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  1. Qian-Hua Li
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  2. Lie Dai
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Correspondence to Lie Dai.

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Li, QH., Dai, L., Li, ZX. et al. Questionnaire survey evaluating disease-related knowledge for 149 primary gout patients and 184 doctors in South China. Clin Rheumatol 32, 1633–1640 (2013). https://doi.org/10.1007/s10067-013-2333-0

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  • DOI: https://doi.org/10.1007/s10067-013-2333-0

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