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The Rotterdam Study: 2014 objectives and design update

  • STUDY UPDATE
  • Published:
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Abstract

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, oncological, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in over a 1,000 research articles and reports (see www.erasmus-epidemiology.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

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Acknowledgments

The Rotterdam Study is supported by the Erasmus MC University Medical Center and Erasmus University Rotterdam; The Netherlands Organisation for Scientific Research (NWO); The Netherlands Organisation for Health Research and Development (ZonMw); the Research Institute for Diseases in the Elderly (RIDE); The Netherlands Genomics Initiative (NGI); the Ministry of Education, Culture and Science; the Ministry of Health, Welfare and Sports; the European Commission (DG XII); and the Municipality of Rotterdam. The contribution of inhabitants, general practitioners and pharmacists of the Ommoord district to the Rotterdam Study is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands

    Albert Hofman, Cornelia M. van Duijn, Oscar H. Franco, M. Arfan Ikram, Caroline C. W. Klaver, Bruno H. Ch. Stricker, Henning W. Tiemeier, André G. Uitterlinden & Meike W. Vernooij

  2. Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

    Sarwa Darwish Murad, Robin P. Peeters, Bruno H. Ch. Stricker & André G. Uitterlinden

  3. Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands

    M. Arfan Ikram

  4. Department of Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands

    Henning W. Tiemeier

  5. Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands

    Oscar H. Franco

  6. Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands

    M. Arfan Ikram & Meike W. Vernooij

  7. Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands

    Caroline C. W. Klaver

  8. Department of Gastro-Enterology, Erasmus Medical Center, Rotterdam, The Netherlands

    Sarwa Darwish Murad

  9. Department of Otolaryngology, Erasmus Medical Center, Rotterdam, The Netherlands

    André Goedegebure

  10. Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands

    Tamar E. C. Nijsten

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  1. Albert Hofman
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  13. Meike W. Vernooij
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Correspondence to Albert Hofman.

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Hofman, A., Murad, S.D., van Duijn, C.M. et al. The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol 28, 889–926 (2013). https://doi.org/10.1007/s10654-013-9866-z

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  • DOI: https://doi.org/10.1007/s10654-013-9866-z

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