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Viscosupplementation for grade II osteoarthritis of the ankle: a prospective study at 18 months’ follow-up

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Abstract

Background

Viscosupplementation, with hyaluronan derivates injected into the intra-space of osteoarthritic joints, is now widely used for the treatment of knee osteoarthritis. This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle.

Methods

Twenty-one patients with a painful ankle and radiographic evidence of grade II osteoarthritis had three weekly intra-articular injections of 2 ml of hylan G-F 20 (10 mg/ml) into the ankle joint. The primary clinical outcome measurement was the ankle osteoarthritis score (AOS) at the baseline, and at 6, 12 and 18 months.

Results

Significant improvement of the AOS from baseline was seen after 6 months (p=0.0001). This improvement was maintained over time with no further changes at 12- and 18-month follow-ups. Regarding pain, the AOS improved over time from the baseline to the 18-month follow up and became statistically significant at the 12- and 18-month follow-ups (p<0.05).

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Authors and Affiliations

  1. School of Physical Therapy and Rehabilitation, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy

    Deianira Luciani

  2. School of Orthopaedics, Istituto Ortopedico Rizzoli, Bologna, Italy

    Matteo Cadossi, Federico Tesei, Eugenio Chiarello & Sandro Giannini

Authors
  1. Deianira Luciani
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  2. Matteo Cadossi
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  3. Federico Tesei
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  4. Eugenio Chiarello
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  5. Sandro Giannini
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Correspondence to Deianira Luciani.

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Luciani, D., Cadossi, M., Tesei, F. et al. Viscosupplementation for grade II osteoarthritis of the ankle: a prospective study at 18 months’ follow-up. Chir Organi Mov 92, 155–160 (2008). https://doi.org/10.1007/s12306-008-0066-z

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  • DOI: https://doi.org/10.1007/s12306-008-0066-z

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