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Bone diseases

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IL-6 receptor inhibition may induce bone erosion repair in RA

Hand bones

Patients with early rheumatoid arthritis who are treated with the interleukin-6 receptor inhibitor tocilizumab experience more pronounced repair of bone erosions than those given adalimumab plus methotrexate, indicate findings from the REBONE study.

medwireNews top story

Opioids, SSRIs, glucocorticoids implicated in RA fracture risk

X-ray of hip fracture (used with permission)

US research shows that the use of opioids, selective serotonin reuptake inhibitors, or glucocorticoids may increase the risk for all types of osteoporotic fracture in patients with rheumatoid arthritis.

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Long-term drug treatment may reduce fracture risk in women with osteoporosis

Osteoporosis

Findings from a systematic review suggest that long-term drug treatment is associated with a reduction in fracture risk among women with osteoporosis, with different agents having varying long-term safety profiles.

Case report

Early-onset osteoarthritis in association with familial angel-shaped phalango-epiphyseal dysplasia previously referred to as peripheral dysostosis

Figure 1

Editorial board member Oliver FitzGerald presents a family with two siblings having features consistent with angel-shaped phalango-epiphyseal dysplasia (ASPED), and a mother with a normal phenotype but with severe, early-onset multi-joint osteoarthritis.

Expert opinion editorial

Osteoporosis therapy: Drug holiday or not?

Osteoporosis (illustration)

Malachi McKenna explains the risks of long-term bisphosphonate therapy in patients with osteoporosis, and the rationale for a drug holiday. He also compares bisphosphonates with denosumab, and explains why denosumab should not be followed by a drug holiday.

31-05-2018 | Osteoporosis | View from the clinic | Article

Monitoring bone health with dual-energy X-ray absorptiometry in pediatric patients

Advisory board member and consultant endocrinologist Malachi McKenna summarizes the use of dual-energy X-ray absorptiometry in monitoring bone health and diagnosing low bone mineral mass in children.

31-05-2018 | Osteoporosis | View from the clinic | Article

Managing osteoporosis in pediatric patients

Editorial board member Sangeeta Sule discusses the causes of low bone mineral density and osteoporosis in pediatric patients with rheumatic diseases, and suggests strategies for risk prevention and treatment of this disease.

08-11-2017 | Osteoporosis | ACR/ARHP 2017 | Video

Expert commentary: Bisphosphonate drug holidays and fracture risk

Linda Russell gives an independent comment on a study showing that suspending bisphosphonate treatment for more than 2 years is associated with increased fracture risk.

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Journal articles and book chapters

04-12-2018 | Comorbidities | Article

Prevalence of comorbidities in systemic sclerosis versus rheumatoid arthritis: a comparative, multicenter, matched-cohort study

Panopoulos S et al. Arthritis Res Ther 2018. doi: 10.1186/s13075-018-1771-0

19-11-2018 | Osteoporosis | Article

Risk of subsequent fracture after prior fracture among older women

Balasubramanian A et al. Osteoporos Int 2018. doi: 10.1007/s00198-018-4732-1

30-07-2018 | Osteoporosis | Review | Article

Glucocorticoid-induced osteoporosis: Update on management

Jagpal A, Saag KG. Curr Treat Options in Rheum 2018. doi: 10.1007/s40674-018-0105-3

Guidelines

A convenient single access point, providing rheumatology professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Images and illustrations

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for rheumatology healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within rheumatology management, as recommended by our Editorial Board.

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