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Gout and crystal arthropathies

Audits on gout management: Far from excellence, but working on it

Audits on gout management

Editorial Board member Fernando Pérez-Ruiz analyzes recent audits on the management of gout in primary and secondary care, and suggests strategies to improve clinical practice.

‘Reassuring’ findings on fracture risk in patients with gout


Results of a large observational study suggest that patients with gout do not have an elevated risk for fragility fractures.

Verinurad–febuxostat combination shows promise for the treatment of gout


Results of a phase IIa trial support further investigation of the selective URAT1 inhibitor verinurad in combination with febuxostat for the treatment of gout.

CARES trial published: Increased cardiovascular death risk with febuxostat


Results of the CARES trial indicate that febuxostat is associated with a higher risk for all-cause and cardiovascular mortality than allopurinol among patients with gout and a history of cardiovascular disease.

Gout as a risk factor for osteoporosis: Epidemiologic evidence from a population-based longitudinal study involving 108,060 individuals

Male patient with gout

Kok VC et al. Osteoporos Int 2018; Advance online publication. doi: 10.1007/s00198-018-4375-2

21-02-2018 | Gout | Editorial | Article

Gout therapies and cardiovascular risk

Editorial Board member Fernando Pérez-Ruiz highlights recent clinical trials evaluating the effect of febuxostat on risk of cardiovascular comorbidities, and discusses alternative treatments for gout patients with cardiovascular disease.

30-10-2017 | Gout | Editorial | Article

Evolution or revolution in urate-lowering therapies for gout?

Editorial Board member Fernando Pérez-Ruiz reflects on changing concepts in the understanding of gout, and reviews the latest developments in new urate-lowering medications for the management of gout.

18-07-2017 | Gout | Editorial | Article

The future of gout: Are you ready for it?

Editorial Board member Fernando Pérez-Ruiz discusses the recent increase in gout-related hospitalizations and asks if we are ready for a future of clinical inertia and passivity when it comes to the management of gout.

Themed collections

30-10-2017 | Gout | Themed collection | Collection

Urate-lowering therapies in gout

This content collection provides an overview of the pathogenesis of gout, followed by a review of current urate-lowering therapies, with an emphasis on their comparative safety and efficacy.

Journal articles and book chapters

04-06-2018 | Inflammation | Review | Article

Novel insights into the role of inflammasomes in autoimmune and metabolic rheumatic diseases

Deuteraiou K et al. Rheumatol Int 2018. doi: 10.1007/s00296-018-4074-5

01-06-2018 | Gout | Article

Gout and the risk of myocardial infarction in older adults: A study of Medicare recipients

Singh JA, Cleveland JD. Arthritis Res Ther 2018; 20: 109. doi: 10.1186/s13075-018-1606-z

01-06-2018 | Gout | Article

Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricemia: A phase 2a, open-label study

Shiramoto M et al. Rheumatology (Oxford) 2018: key100. doi: 10.1093/rheumatology/key100

01-06-2018 | Gout | Article

Comorbidity in gout at the time of first diagnosis: Sex differences that may have implications for dosing of urate lowering therapy

Drivelegka P et al. Arthritis Res Ther 2018; 20: 108. doi: 10.1186/s13075-018-1596-x


A convenient single access point, providing rheumatology professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Images and illustrations

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for rheumatology healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within rheumatology management, as recommended by our Editorial Board.

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