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NSAIDs contribute ‘substantially’ to increased CVD risk in osteoarthritis

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People with osteoarthritis have a significantly higher risk for developing cardiovascular disease than those without, and the use of nonsteroidal anti-inflammatory drugs mediates a considerable proportion of this association, researchers report.

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Partial knee replacement recommended for medial compartment osteoarthritis

Knee arthroplasty concept image (symbolic image with model)

Partial knee replacement is more cost-effective than total knee replacement over 5 years for patients with late-stage isolated medial compartment osteoarthritis of the knee, show results of the TOPKAT trial published in The Lancet.

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Home-based rehabilitation ‘appropriate’ after uncomplicated TKR


Clinic-based or inpatient rehabilitation programs are not superior to home-based programs for individuals who undergo total knee replacement without complications, suggests a systematic review and meta-analysis.

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Biomarker panel may help differentiate PsA from osteoarthritis

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A panel of four soluble biomarkers comprising markers of cartilage metabolism, metabolic syndrome, and inflammation could distinguish psoriatic arthritis from osteoarthritis, researchers report.

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Tramadol linked to increased mortality risk in osteoarthritis patients

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Mortality rates are significantly higher during the first year after a tramadol prescription than after prescription of common nonsteroidal anti-inflammatory drugs, but it is unclear whether the relationship is causal, say researchers.

Journal articles and book chapters


A convenient single access point, providing rheumatology professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Images and illustrations

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for rheumatology healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within rheumatology management, as recommended by our Editorial Board.

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