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Asymptomatic Monosodium Urate Crystal Deposition Associates with Increased Expression of Pro-Inflammatory Genes

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Tuesday, November 12, 17:15–17:30. Georgia World Congress Center, Atlanta, USA

Presenting author: Gabriela Sandoval Plata, UK

What our Editorial Board said:

It has been hypothesized that monosodium urate (MSU) crystals may induce chronic, subclinical inflammatory responses in the absence of acute inflammation. This may explain, at least in part, the association of MSU crystal deposition and increased vascular risk. This study intends to link inflammasome-related genes in a sample of patients with asymptomatic MSU crystal deposits.

The results indicate differences in immune-associated gene expression, suggesting that asymptomatic MSU crystal deposits may have an impact on systemic inflammation.


– Fernando Pérez-Ruiz, Spain

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