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NSAIDs 

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  1. 24-11-2020 | COVID-19 | Highlight | Teaser
    medwireNews top story

    NSAIDs unlikely to increase COVID-19 susceptibility in people with osteoarthritis

    Among patients with osteoarthritis, the risk for COVID-19 is not increased with the use of NSAIDs versus comparator analgesics, study findings indicate.

  2. 24-11-2020 | COVID-19 | News | Article

    NSAIDs unlikely to increase COVID-19 susceptibility in people with osteoarthritis

    Among patients with osteoarthritis, the risk for COVID-19 is not increased with the use of NSAIDs versus comparator analgesics, study findings indicate.

  3. 08-08-2019 | Osteoarthritis | Highlight | Teaser
    medwireNews top story

    NSAIDs contribute ‘substantially’ to increased CVD risk in osteoarthritis

    People with osteoarthritis have a significantly higher risk for developing cardiovascular disease than those without, and the use of nonsteroidal anti-inflammatory drugs mediates a considerable proportion of this association, researchers report.

  4. 08-08-2019 | Osteoarthritis | News | Article

    NSAIDs contribute ‘substantially’ to increased CVD risk in osteoarthritis

    Nonetheless, they note that other studies support the association between NSAIDs and CVD risk, indicating that “the mediating effect of NSAIDs in OA-CVD relationship observed in the study appears to be plausible.”

  5. 05-04-2019 | Osteoarthritis | News | Article

    Beneficial effects of NSAIDs peak early in knee osteoarthritis

    A meta-analysis of 72 randomized controlled trials including 26,424 participants with knee osteoarthritis suggests that the beneficial pain-relief effects of oral NSAIDs peak at 2 weeks, while minor adverse events begin to appear at 4 weeks.

  6. 08-06-2018 | Osteoarthritis | Article

    Disease-modifying effects of COX-2 selective inhibitors and non-selective NSAIDs in osteoarthritis: A systematic review

    Nakata K et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.05.021

  7. 08-06-2022 | EULAR 2022 | Conference coverage | Article

    NSAID suppression of axSpA spinal progression greatest with COX-2 selective inhibitors

    Ten-year results from the GESPIC study support the use of NSAIDs for reducing radiographic spinal progression in patients with axial spondyloarthritis and suggest a stronger effect with cyclo-oxygenase-2 selective inhibitors than non-selective NSAIDs.

  8. 26-07-2022 | Osteoarthritis | News | Article

    Botulinum toxin A injection may ease base-of-thumb osteoarthritis pain

    However, there was no significant difference in pain between the two groups at 6 months nor were there differences in other secondary outcomes, such as change in Cochin Hand Function Scale score and patient global assessment, OARSI-OMERACT response, and the use of analgesics or NSAIDs, at 3 or 6 months.

  9. 27-05-2022 | Myositis | News | Article

    Pain and opioid use common in myositis

    Nearly all patients with myositis report current or past pain, which is often treated with opioids, shows a survey by the patient-led advocacy organization Myositis Support and Understanding.

  10. 15-03-2022 | Juvenile idiopathic arthritis | News | Article
    guidelinesWatch

    ACR issues two updated guidelines for JIA treatment

    “For many years, treatment of JIA consisted of corticosteroids, non-steroidal anti-inflammatory drugs [NSAIDs], physical therapy, bracing and surgery,” said lead author Karen Onel (Hospital for Special Surgery, New York, USA) in a press release.

  11. 16-08-2021 | Temporal cell arteritis | Teaser

    New additions to the Adis Journal Club

    A monthly selection of topical peer-reviewed articles from the Adis journals, curated by the editors.

  12. 16-01-2022 | Hyaluronic acid injection | Adis Journal Club | Article
    Advances in Therapy

    Hyaluronic Acid Therapy in Hip OA Does Not Perform Equally in Osteoarthritis Secondary to Juvenile Idiopathic Arthritis When Compared to Primary Osteoarthritis: A 2-Year Preliminary Evaluation

    Viscosupplementation led to an early and significant improvement of pain and function and concomitant decrease in NSAIDs consumption, while the response diverged over 1 year with loss of benefits in JIA.

  13. 08-02-2022 | Temporal cell arteritis | Teaser

    Rituximab and rheumatology practice in the COVID-19 era

    How can rheumatologists respond to the challenges associated with rituximab use during the pandemic?

  14. 14-10-2021 | Osteoarthritis | News | Article

    Network meta-analysis compares analgesic regimens for osteoarthritis

    A systematic review and network meta-analysis has compared different drug treatments for pain relief in people with knee or hip osteoarthritis, finding that certain NSAIDs may have the greatest benefit, while opioids are associated with increased risk for harm.

  15. 13-12-2021 | Osteoarthritis | News | Article
    News in brief

    Knee replacement linked to reduced MACE, mortality risk in people with osteoarthritis

    People with osteoarthritis  who undergo total knee replacement may have a lower risk for major adverse cardiovascular events  and mortality than those who do not, researchers report.

  16. 24-05-2021 | ACR 2021 | Teaser

    ACR Convergence 2021 highlights

    3–9 November: Keep up with the latest news and interviews from the conference.

  17. 06-09-2021 | Pneumonia | Teaser

    Anifrolumab for the treatment of lupus

    Perspective on the approval of anifrolumab and the importance of endpoints in lupus trials.

  18. 04-03-2021 | Psoriatic arthritis | Adis Journal Club | Article
    Drugs

    Secukinumab: A Review in Psoriatic Arthritis

    In the phase III FUTURE trials, secukinumab 150 or 300 mg improved the clinical signs and symptoms of PsA versus placebo in patients with active disease despite previous treatment with NSAIDs, biological disease-modifying anti-rheumatic drugs (bDMARDs) and/or tumour necrosis factor inhibitors (TNFi).

  19. 18-06-2021 | Axial spondyloarthritis | News | Article
    approvalsWatch

    IL-17A inhibitors supported for axSpA in the UK

    Previously supported for ankylosing spondylitis in the UK, the agent may now also be given  to people with nonradiographic axSpA and objective signs of inflammation who have an inadequate response to NSAIDs.

  20. 22-06-2021 | Osteoarthritis | News | Article

    NSAID use, limited physical activity linked to knee OA progression risk

    medwireNews : Using nonsteroidal anti-inflammatory drugs (NSAIDs) and not meeting physical activity guidelines are both modifiable clinical risk factors for radiographic progression among people with knee osteoarthritis (OA), say researchers.

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