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8 search results for:

Uricosuric agents 

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  1. 21-06-2018 | Gout | Review | Article

    Predicting response or non-response to urate-lowering therapy in patients with gout

    The authors review the extent of treatment success or failure with the xanthine oxidoreductase inhibitors allopurinol and febuxostat and indicate how the dosage of urate-lowering therapy may be modified to increase the response in the majority of patients with gout. Graham GG et al. Curr Rheumatol Rep 2018; 20: 47. doi: 10.1007/s11926-018-0760-2

  2. 21-06-2018 | Gout | Highlight | Teaser
    Journal article

    Predicting response or non-response to urate-lowering therapy in patients with gout

    The authors review the extent of treatment success or failure with the xanthine oxidoreductase inhibitors allopurinol and febuxostat and indicate how the dosage of urate-lowering therapy may be modified to increase the response in the majority of patients with gout [ read more ]. Graham GG et al. Curr Rheumatol Rep 2018; 20: 47. doi: 10.1007/s11926-018-0760-2

  3. 13-02-2018 | Gout | Review | Article

    Managing gout in the patient with renal impairment

    Pascual E, Sivera F, Andrés M. Drugs Aging 2018; Advance online publication. doi: 10.1007/s40266-018-0517-7

  4. 30-10-2017 | Gout | Editorial | Article

    Evolution or revolution in urate-lowering therapies for gout?

    Whilst combination therapy has previously been mostly empiric and based on small, open-label, non-comparative studies; the advent of lesinurad, a uricosuric medication labeled to be used in combination with xanthine oxidase inhibitors, has resulted in three double-blind combination therapy trials.

  5. 08-09-2016 | Gout | Article

    Comparative efficacy and safety of urate-lowering therapy for the treatment of hyperuricemia: a systematic review and network meta-analysis

    Therefore, it is also worthwhile to discuss the efficacy and safety of uricosuric agents and uricase.

  6. 29-09-2015 | Gout | Article

    Allopurinol hypersensitivity: investigating the cause and minimizing the risk

    Alternative agents Importantly, the indications for allopurinol should be considered.

  7. 30-05-2014 | Gout | Book Chapter | Article

    Physiopathology of gout

    The majority of the drugs known to exert a significant uricosuric effect share the ability to inhibit URAT1.

  8. 26-09-2014 | Gout | Article

    Urate-lowering therapy: current options and future prospects for elderly patients with gout

    This paper discusses the use of urate-lowering therapies in elderly patients, with a focus on the available therapeutic options and their risks and benefits in this patient population, as well as a mention of pipeline therapeutics. Stamp LK, Chapman PT.  Drugs Aging . 2014;31:777–786. doi: 10.1007/s40266-014-0214-0.

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