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Connective tissue diseases

medwireNews top story

Elevated IFN-α linked to relapse risk in SLE

Blood sample

A quarter of patients in remission for systemic lupus erythematosus have elevated serum interferon-α levels and may be at increased risk for relapse, French researchers report.

medwireNews top story

Preliminary trial results support further investigation of low-dose IL-2 therapy for SLE

Doctor and needle

The low-dose recombinant IL-2 therapy aldesleukin has a favorable safety profile and may restore regulatory T-cell homeostasis in people with systemic lupus erythematosus, suggest findings from a proof-of-concept phase I/IIa clinical trial.

Expert Opinion: Editorial

Neuropsychiatric systemic lupus erythematosus: Issues in diagnosis and management

Human brain digital illustration

Antigone Pieta, Dionysis Nikolopoulos, and Antonis Fanouriakis discuss the causes and management of neuropsychiatric systemic lupus erythematosus, and outline unmet needs in the diagnosis and treatment of this disease.

medwireNews top story

Pregnancy outcomes improving for women with SLE

Pregnant woman with doctor (symbolic image with model)

In the past two decades pregnancy outcomes, including in-hospital maternal mortality, have improved among women with systemic lupus erythematosus, but further improvements are needed to reduce risks further, US research shows.

Expert Opinion: Editorial

Systemic lupus erythematosus: Novel therapies and targeted treatments


Andrea Fava and George Stojan review new strategies and agents for the treatment of systemic lupus erythematosus that have most recently showed promise in clinical trials.

Themed collections

11-06-2017 | Comorbidities | Themed collection | Collection

Comorbidities in rheumatic disease

This content collection provides an overview of important comorbidities, including cardiovascular disease, mental health, lung disease, fatigue, malignancy and infection, in patients with rheumatic diseases, with a focus on underlying mechanisms.

Journal articles and book chapters

14-12-2018 | Pediatric | Article

Off-label use of tocilizumab to treat non-juvenile idiopathic arthritis in pediatric rheumatic patients: a literature review

Jung JY et al. Pediatr Rheumatol 2018; 16: 79. doi: 10.1186/s12969-018-0296-z

11-12-2018 | Systemic lupus erythematosus | Article

New therapeutic strategies in systemic lupus erythematosus management

Gatto M et al. Nat Rev Rheum 2018. doi: 10.1038/s41584-018-0133-2

04-12-2018 | Comorbidities | Article

Prevalence of comorbidities in systemic sclerosis versus rheumatoid arthritis: a comparative, multicenter, matched-cohort study

Panopoulos S et al. Arthritis Res Ther 2018. doi: 10.1186/s13075-018-1771-0

20-11-2018 | Myositis | Article

Long-term follow-up of autologous hematopoietic stem cell transplantation for refractory juvenile dermatomyositis: A case-series study

Zhu J et al. Pediatr Rheumatol 2018; 16: 72. doi: 10.1186/s12969-018-0284-3


A convenient single access point, providing rheumatology professionals with links to a comprehensive set of clinical practice guidelines from a wide range of relevant organizations.

Images and illustrations

Downloadable PowerPoint slide sets containing a variety of high-quality images and illustrations from Springer Nature’s library of published figures.

Practice tips

Practical information, guidance, and helpful resources for rheumatology healthcare providers. Comprised of practical approaches, case studies, and more.

Themed collections

Compendia of selected, recently published, free full-text journal and book content from Springer Nature and other publishers on a particular topic within rheumatology management, as recommended by our Editorial Board.

Image Credits