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BTK inhibitors 

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  1. 06-05-2022 | Rheumatoid arthritis | News | Article

    Adding BTK inhibitor to upadacitinib offers no benefit in RA

    Treatment with a fixed-dose combination of the novel BTK inhibitor elsubrutinib and the JAK inhibitor upadacitinib offers no additional benefit over upadacitinib alone for people with rheumatoid arthritis, suggest phase 2 trial results.

  2. 16-08-2021 | Temporal cell arteritis | Teaser

    New additions to the Adis Journal Club

    A monthly selection of topical peer-reviewed articles from the Adis journals, curated by the editors.

  3. 08-02-2022 | Temporal cell arteritis | Teaser

    Rituximab and rheumatology practice in the COVID-19 era

    How can rheumatologists respond to the challenges associated with rituximab use during the pandemic?

  4. 24-05-2021 | ACR 2021 | Teaser

    ACR Convergence 2021 highlights

    3–9 November: Keep up with the latest news and interviews from the conference.

  5. 06-09-2021 | Pneumonia | Teaser

    Anifrolumab for the treatment of lupus

    Perspective on the approval of anifrolumab and the importance of endpoints in lupus trials.

  6. 26-10-2020 | Vitamin D | Teaser

    Get ready for ACR Convergence 2020

    5 – 9 November: Preview the conference with session recommendations and updates on upcoming coverage.

  7. 10-05-2021 | Temporal cell arteritis | Teaser

    Febuxostat and cardiovascular risk in people with gout

    How will the FAST trial results impact regulatory guidance & clinical practice?

  8. 18-11-2020 | Temporal cell arteritis | Teaser

    Telemedicine in rheumatology

    Experts discuss the increasing use of telemedicine in rheumatology during the COVID-19 pandemic.

  9. 11-11-2020 | ACR 2020 | Conference coverage | Article

    Evobrutinib fails to improve response rate in refractory RA patients

    “Whilst targeting BTK seems safe and well tolerated, this did not appear to be a significantly effective approach in improving the signs and symptoms of patients with rheumatoid arthritis,” Buch commented.

  10. 18-11-2019 | Systemic lupus erythematosus | ACR/ARP 2019 | Article

    No benefit of add-on fenebrutinib for patients with SLE

    However, despite this lack of efficacy, fenebrutinib resulted in “maximal inhibition of a BTK-dependent pathway biomarker at [week] 48,” reported Isenberg.

  11. 13-06-2019 | Rheumatoid arthritis | News | Article

    Positive results for fenebrutinib in patients with biologic DMARD refractory RA

    Fenebrutinib has shown efficacy for reducing rheumatoid arthritis activity in patients with an inadequate response to either methotrexate or tumor necrosis factor inhibitors, phase II study findings show.

  12. 14-06-2019 | Rheumatoid arthritis | EULAR 2019 | Article

    Expert commentary: Fenebrutinib in RA

    Roy Fleischmann gives his thoughts on the phase IIb fenebrutinib findings in patients with biologic DMARD-refractory rheumatoid arthritis (1:09).

  13. 13-06-2019 | Fenebrutinib | EULAR 2019 | Teaser
    EULAR 2019

    Fenebrutinib in refractory RA

    News story |  Positive results for fenebrutinib in patients with biologic DMARD refractory RA Researcher comment | WATCH: The lead investigator discusses the findings Expert commentary : WATCH: Rheumatologist Roy Fleischmann's view of the findings

  14. 12-06-2019 | Rheumatoid arthritis | EULAR 2019 | Article

    Researcher comment: Phase IIb study of fenebrutinib in RA patients

    Stanley Cohen discusses the key results for the multi-dose trial of fenebrutinib versus placebo and adalimumab in patients with rheumatoid arthritis refractory to methotrexate or prior tumor necrosis inhibitor therapy (2:05).

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