The study included 208 participants who were given an intra-articular injection of the microsphere-based formulation of TA at a dose of 32 mg, followed by a second injection 12, 16, 20, or 24 weeks later.

Results of an observational study suggest that intra-articular corticosteroid injections are associated with an increased risk for progression of knee osteoarthritis.

Recurrent intra-articular corticosteroid injections are often inferior to other injectables, including placebo, for the long-term improvement of pain, function, and quality of life in people with osteoarthritis, meta-analysis data suggest.

A single ultrasound-guided corticosteroid and local anesthetic intra-articular hip injection offers greater pain relief to people with moderate hip osteoarthritis than the best current treatment of advice and education, research suggests.

Intramuscular glucocorticoid injection is noninferior to intra-articular injection for reducing knee pain after 8 and 24 weeks in patients with knee osteoarthritis, but may be inferior at 4 weeks, research shows.

Add-on treatment with an IL-6 receptor inhibitor warrants further investigation for patients with severe COVID-19 pneumonia and systemic hyperinflammation, suggest preliminary findings from two Italian observational studies published in the Annals of the Rheumatic Diseases .

A flare was defined as having been documented as such in patients’ medical notes or a patient being given a new or increased corticosteroid dose.

The corresponding rates of infections were 69.4%, 73.0%, 75.8%, and 64.5%, and a respective 11.3%, 19.0%, 9.7%, and 6.5% experienced injection site reactions.

Christopher Edwards discusses the latest evidence and shares his opinion on tapering therapy in patients with rheumatoid arthritis.

The authors provide an overview of temporomandibular joint involvement in children with juvenile idiopathic arthritis, including imaging methods for diagnosis, clinical examination recommendations, and treatment options.

Treatment options Local therapy options include corticosteroid injections, and lavage with or without corticosteroids.

Appreciate the uniqueness of the temporomandibular joint (TMJ). Appreciate that caution is needed for using intra-articular corticosteroid injections in the TMJ. Understand that treatment of TMJ arthritis and TMJ involvement in JIA includes a multidisciplinary approach.

Jones IA et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0123-4

ART treatments included in vitro fertilization, with or without fertilization with intracytoplasmic sperm injection, and transfer of frozen-thawed embryos.

The researchers conclude in Rheumatology : “These findings support previously identified disruption of glycaemic control with TAcs in diabetic patients; this is the first study to show negligible effects on [glucose levels] after an [intra-articular] corticosteroid (TA-ER) injection.

While some people prefer administering treatment at home, others may experience anxiety related to self-injection or “prefer the additional interactions with health care providers when receiving an [intravenous] medication,” they believe.