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Pathophysiology 

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  1. 14-04-2022 | MIS-C | News | Article

    IL-1Ra autoantibodies may contribute to MIS-C pathophysiology

    Autoantibodies against IL-1Ra are present in a large proportion of patients with MIS-C, say researchers.

  2. 15-05-2018 | Systemic lupus erythematosus | Review | Article

    Monogenic systemic lupus erythematosus: Insights in pathophysiology

    Batu ED. Rheumatol Int 2018. doi: 10.1007/s00296-018-4048-7

  3. 07-11-2017 | Psoriatic arthritis | Image

    Pathophysiology and etiology

  4. 29-09-2016 | Gout | Review | Article

    Gout and osteoarthritis: Associations, pathophysiology, and therapeutic implications

    This review provides an overview of possible biochemical, mechanical, and immunological relationships between gout and osteoarthritis, and the implications of these relationships for treatment. Yokose C et al. Curr Rheumatol Rep 2016;18:65. doi:10.1007/s11926-016-0613-9

  5. 01-01-2016 | Osteoporosis | Book Chapter | Article

    Osteoporosis: Pathophysiology and epidemiology

    This chapter explores the epidemiology of osteoporosis and fragility fracture, cell biology and biomechanics, and the latest research on global trends in age- and sex-specific fracture rates. Moon RJ, Cooper C, Harvey NC. In: The Duration and Safety of Osteoporosis Treatment . Edited by Silverman S, Abrahamsen B. Springer International Publishing Switzerland, 2016. doi:10.1007/978-3-319-23639-1_1

  6. 01-11-2022 | Systemic lupus erythematosus | News | Article

    Dapagliflozin may warrant further investigation for SLE

    They add that “SGLT2 [inhibitors] might further contribute to reducing inflammation, modulating endothelial dysfunction and decelerating atherosclerosis, which are all relevant to the pathophysiology of SLE.”

  7. 20-09-2022 | Rheumatoid arthritis | News | Article
    News in brief

    Study identifies risk factors for mortality in RA-ILD

    They conclude in RMD Open that further research should “study the pathophysiology link between [diabetes] and RA-ILD as well as the effect of RA treatments on RA-ILD progression and mortality.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group RMD Open 2022; 8 : e002343

  8. 23-08-2022 | Systemic lupus erythematosus | News | Article

    LUPIL-2: Aldesleukin warrants further investigation for SLE

    David Klatzmann (Sorbonne Université, Paris, France) and co-investigators explain that insufficiency of Tregs due to a shortage of IL-2 “is central to the pathophysiology” of SLE, but there are currently no approved treatments targeting this pathway.

  9. 21-07-2022 | Granulomatosis with polyangiitis | News | Article

    VTE may be ‘recurrent comorbidity’ in granulomatosis with polyangiitis

    “There is a great need for prospective studies that can further explore the pathophysiology of recurrent VTE and estimate the risks and benefits of prolonged anticoagulation therapy in this unique patient population.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group Rheum Adv Pract 2022; doi:10.1093/rap/rkac058

  10. 16-08-2021 | Temporal cell arteritis | Teaser

    New additions to the Adis Journal Club

    A monthly selection of topical peer-reviewed articles from the Adis journals, curated by the editors.

  11. 08-02-2022 | Temporal cell arteritis | Teaser

    Rituximab and rheumatology practice in the COVID-19 era

    How can rheumatologists respond to the challenges associated with rituximab use during the pandemic?

  12. 24-05-2021 | ACR 2021 | Teaser

    ACR Convergence 2021 highlights

    3–9 November: Keep up with the latest news and interviews from the conference.

  13. 06-09-2021 | Pneumonia | Teaser

    Anifrolumab for the treatment of lupus

    Perspective on the approval of anifrolumab and the importance of endpoints in lupus trials.

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