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CD 

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  1. 27-01-2020 | Rheumatoid arthritis | News | Article

    CDAI nonresponse at 3 months predicts late certolizumab pegol failure in RA

    Real-world findings suggest that nonresponse to certolizumab pegol based on CDAI scores at 3 months is a good indicator that patients with rheumatoid arthritis are unlikely to achieve the therapeutic target of low disease activity at 1 year.

  2. 01-05-2019 | Rheumatoid arthritis | News | Article

    CD40L blockade shows promise for RA

    Findings from a proof-of-concept study provide preliminary evidence that the CD40 ligand binding agent VIB4920 may be a promising treatment option for rheumatoid arthritis.

  3. 25-04-2018 | Giant cell arteritis | Article

    CD3 immunohistochemistry is helpful in the diagnosis of giant cell arteritis

    Ciccia F et al. Rheumatology (Oxford) 2018; Advance online publication. doi: 10.1093/rheumatology/key106

  4. 07-11-2017 | Sjögren’s syndrome | ACR/ARHP 2017 | Article
    News in brief

    CD40 blockade shows promise in Sjögren’s syndrome

    Phase IIa trial results suggest that treatment with the anti-CD40 monoclonal antibody CFZ533 improves disease activity and is well tolerated in patients with clinically active primary Sjögren’s syndrome.

  5. 18-08-2017 | Systemic lupus erythematosus | News | Article

    Hopes revived for CD40L blockade in SLE

    Phase I trial results suggest that the CD40 ligand inhibitor dapirolizumab pegol is well tolerated and elicits a clinical response in patients with systemic lupus erythematosus.

  6. 30-05-2019 | Arthroplasty | News | Article
    approvalsWatch

    FDA approves first diagnostic test for joint replacement infections

    The assay, called the Synovasure Lateral Flow Test Kit (CD Diagnostics Inc., Claymont, Delaware, USA), measures alpha defensins released by neutrophils in the synovial fluid, indicating the presence of infection.

  7. 03-05-2018 | Systemic lupus erythematosus | Article

    Meta-analysis of GWAS on both Chinese and European populations identifies GPR173 as a novel X chromosome susceptibility gene for SLE

    Kaufman KM, Zhao J, Kelly JA, Hughes T, Adler A, Sanchez E, Ojwang JO, Langefeld CD, Ziegler JT, Williams AH, et al.

  8. 06-06-2016 | Gout | Article

    A joint effort over a period of time: factors affecting use of urate-lowering therapy for long-term treatment of gout

    This paper examines reasons for lack of urate-lowering therapy (ULT) in many patients with gout, using patient interviews to explore patient experience with, and understanding of, such therapy. Richardson JC, Liddle J, Mallen CD, Roddy E, Hider S, Prinjha S, Ziebland S.  BMC Musculoskelet Disord . 2016;17:249. doi: 10.1186/s12891-016-1117-5.

  9. 08-02-2016 | Microbiome | Article

    Intestinal Microbiota Distinguish Gout Patients from Healthy Humans

    A non-redundant gene catalogue was constructed with CD-HIT 38 using a sequence indentity cut-off of 0.95, with a minimum coverage cut-off of 0.9 for the shorter sequences.

  10. 13-06-2018 | Osteoarthritis | Review | Article

    Molecular transport in articular cartilage: What have we learned from the past 50 years?

    DiDomenico CD, Lintz M, Bonassar LJ. Nat Rev Rheumatol 2018; 14: 393–403. doi: 10.1038/s41584-018-0033-5

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