Patients with rheumatoid arthritis have reported greater improvements with sarilumab versus adalimumab in multiple outcomes, complementing its superior clinical efficacy profile already reported in the MONARCH trial.

Robson J et al. Ann Rheum Dis 2018; Advance online publication. doi: 10.1136/annrheumdis-2017-212713

The objective of this study was to investigate the clinical presentation of joint and active skin symptom involvement and the associated impact on physician- and patient-reported outcomes, and healthcare resource burden in patients with psoriatic arthritis [ read more ]. de Vlam K et al. Rheumatol Ther 2018. doi: 10.1007/s40744-018-0120-8

Gottlieb AB et al. Rheumatology (Oxford) 2018: key161. doi: 10.1093/rheumatology/key161

The authors determined that although several patient-reported outcomes have been identified additional work is needed to obtain a better insight into the required outcomes that incorporate the patient’s perspective. Rheumatol Int 2016;36:897. doi:10.1007/s00296-015-3416-9

By contrast, patient-reported outcomes, including ESSPRI score, improved to a similar degree in the two treatment groups and there was no differentiation between the two treatments in terms of the ESSPRI subdomains of dryness, pain, and fatigue.

A diet and exercise program delivered in community settings may improve some clinical outcomes for people with knee osteoarthritis and overweight or obesity, suggest findings from the WE-CAN pragmatic randomized controlled trial.

The safety outcomes were “consistent with the well-established safety profiles” for secukinumab and adalimumab biosimilar, Baraliakos reported, with adverse event rates of 79.7%, 81.8%, and 84.2% for patients treated with secukinumab 150 mg and 300 mg and adalimumab biosimilar, respectively. medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ACR Convergence 2022; Philadelphia, Pennsylvania, USA: November 10–14

The two studies among patients with trapeziometacarpal OA showed similar outcomes.

One patient experienced a urinary tract infection and there were no cases of diabetic ketoacidosis.

They say that the symptoms they identified “have meaning for patients in terms of managing their condition,” and may therefore “lead to poor treatment adherence, persistence, increased health care use, and worse clinical and patient outcomes.” medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2022 Springer Healthcare Ltd, part of the Springer Nature Group ACR Open Rheumatol 2022; doi:10.1002/acr2.11467

Pain intensity strongly correlates with disease activity measured by DAS28-ESR in people with rheumatoid arthritis, with the association mostly explained by the patient global assessment element of the composite score, study data show.

As reported in The Journal of Rheumatology , the average number of moderate patient-reported flares (lasting 1–3 days) improved from baseline to week 12 in both groups, from 0.7 to 0.5 in the WAT group and from 1.0 to 0.5 in the control group.

Enthesitis and dactylitis as secondary outcomes were also reviewed.

Women with axial spondyloarthritis have “very low” rates of adverse pregnancy outcomes, show observational data from European pregnancy registries.