Gout

Singh JA, Cleveland JD. BMJ Open 2018; 8: e022854. doi: 10.1136/bmjopen-2018-022854

Tseng CC et al. Arthritis Res Ther 2018; 20: 137. doi: 10.1186/s13075-018-1637-5

The aim of this systematic review and meta-analysis was to assess the risk of incident gout associated with obesity, hypertension and diuretic use.

Evans PL et al. Arthritis Res Ther 2018; 20: 136. doi: 10.1186/s13075-018-1612-1

Zleik N et al. J Rheumatol 2018. doi: 10.3899/jrheum.171320

Coiffier G et al. Clin Rheumatol 2018. doi: 10.1007/s10067-018-4160-9

Drivelegka P et al. Arthritis Res Ther 2018; 20: 108. doi: 10.1186/s13075-018-1596-x

Gunawardhana L et al. Arthritis Res Ther 2018; 20: 99. doi: 10.1186/s13075-018-1593-0

Major TJ et al. Nat Rev Rheumatol 2018; Advance online publication. doi: 10.1038/s41584-018-0004-x

The authors describe four patients with chronic gout who were successfully managed with pegloticase and were retreated following a gap in therapy.

Morton AH, Hosey T, LaMoreaux B. Rheumatol Ther 2018; Advance online publication. doi: 10.1007/s40744-018-0111-9

Fabre S et al. Arthritis Res Ther 2018; 20: 78. doi: 10.1186/s13075-018-1585-0

Jee Y et al. Clin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4118-y

The authors find that the hypothesis that patients with gout may acquire fewer community-acquired infections or have lower infection-related mortality is not supported.

Spaetgens B, de Vries F, Driessen JHM et al. Scientific Reports 2017;7:1429. doi:10.1038/s41598-017-01588-5

The authors find a statistically significant increase in the risk of erectile dysfunction among men with gout, which has important implications in planning a multidisciplinary approach to managing the condition.

Abdul Sultan A, Mallen C, Hayward R et al. Arthritis Res Ther 2017;19:123. doi:10.1186/s13075-017-1322-0

This study finds that the risk of nephrolithiasis in patients with gout is increased by 60% compared to controls, and identifies obesity and use of loop diuretics as potentially modifiable risk factors.

Landgren AJ, Jacobsson LTH, Lindström U et al. Arthritis Res Ther 2017;19:173. doi:10.1186/s13075-017-1376-z

Harold et al. analyze a US national cohort of gout patients and determine that the profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.

Harrold LR et al. BMC Musculoskelet Disord 2017;18:108. doi:10.1186/s12891-017-1465-9

This regression analysis demonstrates that active tobacco use was associated with a lower risk of acute inpatient gouty arthritis, even when controlling for conventional risk factors.

Poudel DR, Karmacharya P, & Donato A. Clin Rheumatol 2016;35:3015–3018. doi:10.1007/s10067-016-3415-6

In this review, data from epidemiological studies from diverse regions of the world are synthesized to depict the geographic variation in gout prevalence and incidence.

Nat Rev Rheumatol 2015;11:649–662. doi:10.1038/nrrheum.2015.91

This chapter discusses etiology, epidemiology, and image diagnosis as well as pathology, pathological differential diagnosis, prognosis, and treatment.

Klein MJ. In: Tumors and Tumor-Like Lesions of Bone. Springer-Verlag London, 2015. doi:10.1007/978-1-4471-6578-1_68