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19-08-2016 | Osteoporosis | Book Chapter | Article

7. Osteoporosis: Pathophysiology and Clinical Aspects

Author: MD Peter Mikosch

Publisher: Springer International Publishing


Osteoporosis has become a major health issue over the last years due to the steadily increasing life expectancy. Osteoporosis is estimated to affect 75 million people in the United States, Europe, and Japan and about 200 million women worldwide – approximately one-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80, and two-thirds of women aged 90. Worldwide, one in three women over age 50 will experience osteoporotic fractures and one in five men aged over 50. Overall, 61 % of osteoporotic fractures occur in women, with a female-to-male ratio of 1.6 (Johnell and Kanis 2006).

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