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Vasculitis

ANCA-associated vasculitis

04-02-2019 | ANCA-associated vasculitis | News

Add-on belimumab does not reduce relapse risk in ANCA-associated vasculitis

The addition of belimumab to maintenance therapy with azathioprine and low-dose glucocorticoids does not improve maintenance of remission among patients with antineutrophil cytoplasmic antibody-associated vasculitis, findings from the BREVAS trial suggest.

15-01-2019 | ANCA-associated vasculitis | News

Randomized data back EULAR guidelines for mycophenolate mofetil use in AAV

Mycophenolate mofetil is noninferior to cyclophosphamide for inducing remission among patients with antineutrophil cytoplasmic antibody-associated vasculitis, randomized trial data show.

B cell therapy in ANCA-associated vasculitis: Current and emerging treatment options

In this review, the theoretical background for use of dual B cell-targeted immunotherapy in anti-neutrophil cytoplasmic antibody-associated vasculitis is presented and discussed [read more].
McClure M et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0065-x

14-08-2018 | ANCA-associated vasculitis | Review | Article

B cell therapy in ANCA-associated vasculitis: Current and emerging treatment options

McClure M et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0065-x

Unusual case of chronic recurrent multifocal osteomyelitis

The authors present a rare case of sporadic chronic recurrent multifocal osteomyelitis in which the patient eventually developed cytoplasmic anti-neutrophil cytoplasmic antibodies-associated renal vasculitis and hyperparathyroidism [read more].
Snipaitiene A et al. Pediatr Rheumatol 2018; 16: 49. doi: 10.1186/s12969-018-0267-4

27-07-2018 | Bone diseases | Case report | Article

Unusual case of chronic recurrent multifocal osteomyelitis

The authors present a rare case of sporadic chronic recurrent multifocal osteomyelitis in which the patient eventually developed cytoplasmic anti-neutrophil cytoplasmic antibodies-associated renal vasculitis and hyperparathyroidism.

Snipaitiene A et al. Pediatr Rheumatol 2018; 16: 49. doi: 10.1186/s12969-018-0267-4

The ongoing evolution of remission maintenance strategies for granulomatosis with polyangiitis

Eric J Gapud and Philip Seo summarize the key milestones in management of severe granulomatosis with polyangiitis, and evaluate the possibility of long-term reduced intensity or drug-free remission for some patients [read more].

20-07-2018 | Granulomatosis with polyangiitis | Editorial | Article

The ongoing evolution of remission maintenance strategies for granulomatosis with polyangiitis

Eric J Gapud and Philip Seo summarize the key milestones in management of severe granulomatosis with polyangiitis, and evaluate the possibility of long-term reduced intensity or drug-free remission for some patients.

05-07-2018 | ANCA-associated vasculitis | News

Trimethoprim–sulfamethoxazole reduces severe infections following rituximab for vasculitis

A study looking at risk factors for the development of severe infections in patients with antineutrophil cytoplasm antibody-associated vasculitis following rituximab has found that trimethoprim–sulfamethoxazole prophylaxis may be of benefit.

03-05-2018 | ANCA-associated vasculitis | Article

Long-term efficacy of remission-maintenance regimens for ANCA-associated vasculitides

Terrier B et al. Ann Rheum Dis 2018; Advance online publication. doi: 10.1136/annrheumdis-2017-212768

25-04-2018 | ANCA-associated vasculitis | Article

Validation of the ANCA-associated vasculitis patient-reported outcomes (AAV-PRO) questionnaire

Robson J et al. Ann Rheum Dis 2018; Advance online publication. doi: 10.1136/annrheumdis-2017-212713

02-04-2018 | Granulomatosis with polyangiitis | Article

Eosinophilic granulomatosis with polyangiitis: Newer therapies

Navarro-Mendoza EP, Tobón GJ. Curr Rheumatol Rep 2018; 20: 23. doi: 10.1007/s11926-018-0736-2

21-03-2018 | Vasculitis | Review | Article

Vasculitis in Africa

Genga E, Oyoo O, Adebajo A. Curr Rheumatol Rep 2018; 20: 4. doi: 10.1007/s11926-018-0711-y

10-03-2018 | ANCA-associated vasculitis | Review | Article

Anti-neutrophil cytoplasmic antibodies and their clinical significance

Suwanchote S et al. Clin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4062-x

20-02-2018 | Granulomatosis with polyangiitis | Article

Ear, nose and throat involvement in granulomatosis with polyangiitis: How it presents and how it determines disease severity and long-term outcomes

Felicetti M et al. Clin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4019-0

22-09-2017 | ANCA-associated vasculitis | News

Active CV risk management needed in ANCA-associated vasculitis

A meta-analysis has highlighted the cardiovascular risk faced by patients with vasculitis associated with the presence of anti-neutrophil cytoplasmic antibodies.

09-08-2017 | ANCA-associated vasculitis | News

‘No clear evidence’ for extending azathioprine maintenance therapy in ANCA-associated vasculitis

A post-hoc analysis of combined trial data suggests that extending azathioprine maintenance therapy beyond 18 months is not necessary for preventing relapses among patients with antineutrophil cytoplasmic autoantibody-associated vasculitis.

07-08-2017 | Vasculitis | Review | Article

Vasculitis update: Pathogenesis and biomarkers

Brogan & Eleftheriou summarize recent advances in the understanding of the pathophysiology of primary systemic vasculitides and the potential role of novel biomarkers discovered in that context. 

Brogan P, Eleftheriou D. Pediatr Nephrol 2017. doi:10.1007/s00467-017-3597-4

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