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Pathophysiology

Pathophysiology

23-08-2022 | Systemic lupus erythematosus | News

LUPIL-2: Aldesleukin warrants further investigation for SLE

Phase 2 trial results suggest that low-dose interleukin-2 therapy with aldesleukin may represent a promising add-on treatment option for systemic lupus erythematosus.

Rituximab and rheumatology practice in the COVID-19 era

How can rheumatologists respond to the challenges associated with rituximab use during the pandemic?

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Anifrolumab for the treatment of lupus

Perspective on the approval of anifrolumab and the importance of endpoints in lupus trials.

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31-08-2021 | Sjögren’s syndrome | News

Early-onset primary Sjögren’s syndrome linked to more severe disease

People who develop early-onset primary Sjögren’s syndrome have “strikingly more severe disease activity” and greater activation of the cellular immune system compared with those diagnosed at a later age, researchers report.

New additions to the Adis Journal Club

A monthly selection of topical peer-reviewed articles from the Adis journals, curated by the editors.

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JAK inhibitor safety

Data summary, expert discussion, & research news on the potential risks associated with JAK inhibitors.

ACR Convergence 2021 highlights

3–9 November: Keep up with the latest news and interviews from the conference.

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Febuxostat and cardiovascular risk in people with gout

How will the FAST trial results impact regulatory guidance & clinical practice?

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Telemedicine in rheumatology

Experts discuss the increasing use of telemedicine in rheumatology during the COVID-19 pandemic.

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Get ready for ACR Convergence 2020

5 – 9 November: Preview the conference with session recommendations and updates on upcoming coverage.

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03-08-2018 | Pathophysiology | Review | Article

S100 proteins in rheumatic diseases

Austermann J, Spiekermann C, Roth J. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0058-9

28-06-2018 | Myositis | Review | Article

Update on inclusion body myositis

Jabari D et al. Curr Rheumatol Rep 2018; 20: 52. doi: 10.1007/s11926-018-0755-z

25-06-2018 | Systemic sclerosis | Review | Article

Update on the gastrointestinal microbiome in systemic sclerosis

Bellocchi C, Volkmann ER. Curr Rheumatol Rep 2018; 20: 49. doi: 10.1007/s11926-018-0758-9

20-06-2018 | Systemic lupus erythematosus | Article

TLR4+CXCR4+ plasma cells drive nephritis development in systemic lupus erythematosus

Ma K et al. Ann Rheum Dis 2018. doi: 10.1136/annrheumdis-2018-213615

13-06-2018 | Systemic lupus erythematosus | Article

Lupus retinopathy: A marker of active systemic lupus erythematosus

Seth G et al. Rheumatol Int 2018. doi: 10.1007/s00296-018-4083-4

08-06-2018 | Pain | Review | Article

Cannabinoids for the treatment of rheumatic diseases: Where do we stand?

Katz-Talmor D et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0025-5

04-06-2018 | Inflammation | Review | Article

Novel insights into the role of inflammasomes in autoimmune and metabolic rheumatic diseases

Deuteraiou K et al. Rheumatol Int 2018. doi: 10.1007/s00296-018-4074-5

31-05-2018 | Systemic sclerosis | Article

Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: Insights from the faSScinate clinical trial in systemic sclerosis

Denton CP et al. Ann Rheum Dis 2018. doi: 10.1136/annrheumdis-2018-213031

30-05-2018 | Systemic lupus erythematosus | Article

Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus

Julià A et al. Arthritis Res Ther 2018; 20: 100. doi: 10.1186/s13075-018-1604-1

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