Juvenile arthritis

Austermann J, Spiekermann C, Roth J. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0058-9

Katz-Talmor D et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0025-5

In this review, Finch et al summarize and evaluate the current literature relating to vitamin D and juvenile idiopathic arthritis.

Finch SL, Rosenberg AM, Vatanparast H. Pediatr Rheumatol 2018; 16: 34. doi: 10.1186/s12969-018-0250-0

Wampler TL, Niewold TB. Nat Rev Rheumatol 2018; 14: 214–228. doi: 10.1038/nrrheum.2018.31

Esmaeili Reykande S et al. iClin Rheumatol 2018; Advance online publication. doi: 10.1007/s10067-018-4010-9

Smitherman EA, Consolaro A, Morgan EM. Curr Treat Options in Rheum 2018; 4: 29–43. doi: 10.1007/s40674-018-0090-6

Barturen G et al. Nat Rev Rheumatol 2018; 14: 75–93. doi: 10.1038/nrrheum.2017.220

The findings of this study suggest a possible role for the lectin pathway in the pathogenesis of juvenile idiopathic arthritis, perhaps secondary to a role in host defense.

Immunol Cell Biol 2017;95:666-675. doi:10.1038/icb.2017.31

A case report reviewing two siblings with severe familial forms of juvenile idiopathic arthritis (JIA) and the causal role of mutations in FAMIN for this and other form of JIA.

Kallinich T et al. Pediatr Rheumatol 2016;14:63. doi:10.1186/s12969-016-0124-2

An expert review of the involvement of the microbiome in juvenile idiopathic arthritis (JIA) pathogenesis and how it may influence the development of autoimmunity in JIA.

Verwoerd A et al. Pediatr Rheumatol 2016;14:55. doi:10.1186/s12969-016-0114-4

Arvonen et al. discuss the mechanisms by which the the microbiota may influence the risk of juvenile idiopathic arthritis and other systemic inflammatory conditions in children.

Arvonen M et al. Pediatr Rheumatol 2016;14:44. doi:10.1186/s12969-016-0104-6

In this study, whole blood expression profiling distinguishes children with polyarticular juvenile idiopathic arthritis from healthy controls and identifies pathways of biologic relevance.

Jiang K et al. Arthritis Res Ther 2016;18:157. doi:10.1186/s13075-016-1059-1

This review highlights findings in systems biology related to juvenile idiopathic arthritis (JIA) in an attempt to assist in the understanding of JIA pathogenesis and therapeutic target identification.

Donn R et al. Pediatr Rheumatol 2016;14:40. doi:10.1186/s12969-016-0078-4